Methods widely used to detect apoptosis do not allow us to easily distinguish between nuclei from viable or necrotic cells. Even if apoptosis and necrosis seem to occur as alternatives at the single cell level, they could be present simultaneously in a cell population much more frequently than expected. For this reason, attention was focused on attempting to recognize, by multiparameter flow cytometry, the characteristics of viable cells and of apoptotic or necrotic dead cells.

Matteucci, C., Grelli, S., De Smaele, E., Fontana, C., Mastino, A. (1999). Identification of nuclei from apoptotic, necrotic, and viable lymphoid cells by using multiparameter flow cytometry. CYTOMETRY, 35(2), 145-153.

Identification of nuclei from apoptotic, necrotic, and viable lymphoid cells by using multiparameter flow cytometry

MATTEUCCI, CLAUDIA;GRELLI, SANDRO;FONTANA, CARLA;MASTINO, ANTONIO
1999-02-01

Abstract

Methods widely used to detect apoptosis do not allow us to easily distinguish between nuclei from viable or necrotic cells. Even if apoptosis and necrosis seem to occur as alternatives at the single cell level, they could be present simultaneously in a cell population much more frequently than expected. For this reason, attention was focused on attempting to recognize, by multiparameter flow cytometry, the characteristics of viable cells and of apoptotic or necrotic dead cells.
1-feb-1999
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore MED/07 - MICROBIOLOGIA E MICROBIOLOGIA CLINICA
English
Con Impact Factor ISI
Phosphatidylserines; Animals; Necrosis; Electrophoresis; Apoptosis; Mice, Inbred C57BL; Mice; Flow Cytometry; Lymphocytes; Cell Nucleus
Matteucci, C., Grelli, S., De Smaele, E., Fontana, C., Mastino, A. (1999). Identification of nuclei from apoptotic, necrotic, and viable lymphoid cells by using multiparameter flow cytometry. CYTOMETRY, 35(2), 145-153.
Matteucci, C; Grelli, S; De Smaele, E; Fontana, C; Mastino, A
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/52559
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