Recombinant clones specific for ribosomal protein (r-protein) S8 have been isolated from a Xenopus laevis cDNA bank. Sequence analysis shows that they are of two types, derived from two different gene copies originating from gene duplication. The two cDNAs differ in several silent sites and code for the same S8 protein whose complete amino acid sequence has been derived. Sequence comparison of S8 mRNAs with those for other X. laevis r-proteins, has revealed interesting similarities in the 5' and 3' untranslated regions. These could be involved in r-protein synthesis regulation which we have previously shown to occur mainly at posttranscriptional and translational levels.

Mariottini P., B.C. (1988). Isolation and nucleotide sequences of cDNAs for Xenopus laevis ribosomal protein S8: Similarities in the 5' and 3' untranslated regions of mRNAs for various r-proteins. GENE, 67(1), 69-74.

Isolation and nucleotide sequences of cDNAs for Xenopus laevis ribosomal protein S8: Similarities in the 5' and 3' untranslated regions of mRNAs for various r-proteins

BAGNI, CLAUDIA;AMALDI, FRANCESCO
1988

Abstract

Recombinant clones specific for ribosomal protein (r-protein) S8 have been isolated from a Xenopus laevis cDNA bank. Sequence analysis shows that they are of two types, derived from two different gene copies originating from gene duplication. The two cDNAs differ in several silent sites and code for the same S8 protein whose complete amino acid sequence has been derived. Sequence comparison of S8 mRNAs with those for other X. laevis r-proteins, has revealed interesting similarities in the 5' and 3' untranslated regions. These could be involved in r-protein synthesis regulation which we have previously shown to occur mainly at posttranscriptional and translational levels.
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore BIO/13
English
Con Impact Factor ISI
complementary dna; messenger rna; radioisotope; ribosome protein; animal cell; egg; female; frog; gene duplication; genetic engineering; heredity; nonhuman; normal value; nucleotide sequence; rna structure; xenopus laevis; Amino Acid Sequence; Animal; Base Sequence; Cloning, Molecular; DNA; DNA Restriction Enzymes; Genes, Structural; Molecular Sequence Data; Ribosomal Proteins; RNA, Messenger; Support, Non-U.S. Gov't; Xenopus laevis
Mariottini P., B.C. (1988). Isolation and nucleotide sequences of cDNAs for Xenopus laevis ribosomal protein S8: Similarities in the 5' and 3' untranslated regions of mRNAs for various r-proteins. GENE, 67(1), 69-74.
Mariottini, P; Bagni, C; Amnesi, F; Amaldi, F
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2108/52190
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