Several new 6-oxiranyl-, 6-methyloxiranyluracils, and pyrimidinone derivatives, synthesized by the lithiation-alkylation sequence of 1,3,6-trimethyluracil, 1,3-dimethyl-6-chloromethyluracil, and 2-alkoxy-6methyl-4(3H)-pyrimidinones, showed a potent and selective antiviral activity against the parainfluenza 1(Sendai) virus replication, (C) 1998 Elsevier Science Ltd. All rights reserved.

Saladino, R., Danti, M., Mincione, E., Crestini, C., Palamara, A., Savini, P., et al. (1998). A potent and selective inhibition of parainfluenza 1 (Sendai) virus by new 6-oxiranyl-, 6-methyloxiranyluracils, and 4(3H)-pyrimidinone derivatives. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 8(14), 1833-1838 [10.1016/S0960-894X(98)00314-X].

A potent and selective inhibition of parainfluenza 1 (Sendai) virus by new 6-oxiranyl-, 6-methyloxiranyluracils, and 4(3H)-pyrimidinone derivatives.

CRESTINI, CLAUDIA;MARINI, STEFANO;
1998-01-01

Abstract

Several new 6-oxiranyl-, 6-methyloxiranyluracils, and pyrimidinone derivatives, synthesized by the lithiation-alkylation sequence of 1,3,6-trimethyluracil, 1,3-dimethyl-6-chloromethyluracil, and 2-alkoxy-6methyl-4(3H)-pyrimidinones, showed a potent and selective antiviral activity against the parainfluenza 1(Sendai) virus replication, (C) 1998 Elsevier Science Ltd. All rights reserved.
1998
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore CHIM/03 - CHIMICA GENERALE E INORGANICA
English
Saladino, R., Danti, M., Mincione, E., Crestini, C., Palamara, A., Savini, P., et al. (1998). A potent and selective inhibition of parainfluenza 1 (Sendai) virus by new 6-oxiranyl-, 6-methyloxiranyluracils, and 4(3H)-pyrimidinone derivatives. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 8(14), 1833-1838 [10.1016/S0960-894X(98)00314-X].
Saladino, R; Danti, M; Mincione, E; Crestini, C; Palamara, A; Savini, P; Marini, S; Botta, M
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/52130
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