The interaction between HIV-1 gp120 and CCR5 N terminus is critical for R5-virus entry and affects CCR5 antagonists' activity. Knowledge of how different genetic signatures of gp120 V3 domain effect the strength of this interaction is limited.
Svicher, V., Alteri, C., Artese, A., Zhang, J., Costa, G., Mercurio, F., et al. (2011). Identification and structural characterization of novel genetic elements in the HIV-1 V3 loop regulating coreceptor usage. ANTIVIRAL THERAPY, 16(7), 1035-1045 [10.3851/IMP1862].
Identification and structural characterization of novel genetic elements in the HIV-1 V3 loop regulating coreceptor usage
SVICHER, VALENTINA;ANDREONI, MASSIMO;CECCHERINI SILBERSTEIN, FRANCESCA;PERNO, CARLO FEDERICO
2011-01-01
Abstract
The interaction between HIV-1 gp120 and CCR5 N terminus is critical for R5-virus entry and affects CCR5 antagonists' activity. Knowledge of how different genetic signatures of gp120 V3 domain effect the strength of this interaction is limited.File in questo prodotto:
| File | Dimensione | Formato | |
|---|---|---|---|
|
Svicher_V3_gen_det_AVT11.pdf
accesso aperto
Licenza:
Copyright dell'editore
Dimensione
397.74 kB
Formato
Adobe PDF
|
397.74 kB | Adobe PDF | Visualizza/Apri |
Questo articolo è pubblicato sotto una Licenza Licenza Creative Commons
