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The aim of this study is to evaluate the influence of germline vascular endothelial growth factor (VEGF) gene polymorphisms (VGPs) on the efficacy of the anti-VEGF antibody bevacizumab (Bev) in metastatic colorectal cancer (MCRC) patients.

Formica, V., Palmirotta, R., Del Monte, G., Savonarola, A., Ludovici, G., De Marchis, M., et al. (2011). Predictive value of VEGF gene polymorphisms for metastatic colorectal cancer patients receiving first-line treatment including fluorouracil, irinotecan, and bevacizumab. INTERNATIONAL JOURNAL OF COLORECTAL DISEASE, 26(2), 143-51 [10.1007/s00384-010-1108-1].

Predictive value of VEGF gene polymorphisms for metastatic colorectal cancer patients receiving first-line treatment including fluorouracil, irinotecan, and bevacizumab

Formica, V;ROSELLI, MARIO
2011-02-01

Abstract

The aim of this study is to evaluate the influence of germline vascular endothelial growth factor (VEGF) gene polymorphisms (VGPs) on the efficacy of the anti-VEGF antibody bevacizumab (Bev) in metastatic colorectal cancer (MCRC) patients.
1-feb-2011
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore MED/01 - STATISTICA MEDICA
English
Con Impact Factor ISI
Male; Aged, 80 and over; Multivariate Analysis; Alleles; Middle Aged; Vascular Endothelial Growth Factor A; Camptothecin; Colorectal Neoplasms; Female; Polymorphism, Single Nucleotide; Fluorouracil; Predictive Value of Tests; Disease-Free Survival; Humans; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Aged; Proportional Hazards Models; Adult; Antibodies, Monoclonal; Neoplasm Metastasis; Pharmacogenetics
Formica, V., Palmirotta, R., Del Monte, G., Savonarola, A., Ludovici, G., De Marchis, M., et al. (2011). Predictive value of VEGF gene polymorphisms for metastatic colorectal cancer patients receiving first-line treatment including fluorouracil, irinotecan, and bevacizumab. INTERNATIONAL JOURNAL OF COLORECTAL DISEASE, 26(2), 143-51 [10.1007/s00384-010-1108-1].
Formica, V; Palmirotta, R; Del Monte, G; Savonarola, A; Ludovici, G; De Marchis, M; Grenga, I; Schirru, M; Guadagni, F; Roselli, M
Articolo su rivista
01 - Articolo su rivista
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/51640
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