We studied the role of endogenous acetylcholine (Ach) in corticostriatal long-term potentiation (LTP). The muscarinic receptor antagonists scopolamine and pirenzepine fully prevented the induction of LTP suggesting that the activation of M1-like muscarinic receptors is a crucial event in the conditioning phase of this form of synaptic plasticity.

Calabresi, P., Centonze, D., Gubellini, P., Bernardi, G. (1999). Activation of M1-like muscarinic receptors is required for the induction of corticostriatal LTP. NEUROPHARMACOLOGY, 38(2), 323-326 [10.1016/S0028-3908(98)00199-3].

Activation of M1-like muscarinic receptors is required for the induction of corticostriatal LTP

CALABRESI, PAOLO;CENTONZE, DIEGO;BERNARDI, GIORGIO
1999-02-01

Abstract

We studied the role of endogenous acetylcholine (Ach) in corticostriatal long-term potentiation (LTP). The muscarinic receptor antagonists scopolamine and pirenzepine fully prevented the induction of LTP suggesting that the activation of M1-like muscarinic receptors is a crucial event in the conditioning phase of this form of synaptic plasticity.
feb-1999
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore MED/26 - NEUROLOGIA
English
Con Impact Factor ISI
Acetylcholine; Corpus Striatum; Male; Pirenzepine; Receptor, Muscarinic M1; Synapses; Rats, Wistar; Receptors, Muscarinic; Rats; Scopolamine; Animals; Cerebral Cortex; Neuronal Plasticity; Muscarinic Antagonists; Neurons; Long-Term Potentiation
Calabresi, P., Centonze, D., Gubellini, P., Bernardi, G. (1999). Activation of M1-like muscarinic receptors is required for the induction of corticostriatal LTP. NEUROPHARMACOLOGY, 38(2), 323-326 [10.1016/S0028-3908(98)00199-3].
Calabresi, P; Centonze, D; Gubellini, P; Bernardi, G
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/51483
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