he authors have studied nasal mucociliary function and adenoid surface characteristics in a group of 86 children, aged between 4 and 10 years, divided in two groups according to the presence or absence of clinical, instrumental and rontgenographic signs of nasal obstruction due to hypertrophied adenoids. Each group was divided into 3 age-related subgroups (group I: 4-5 years; group II: 6-7 years; group III: 8-10 years). A population of normal adults was chosen both for functional and ultrastructural characteristics. Nasal mucociliary clearance velocity values were evaluated by means of the saccharine method and the surface characteristics of the adenoid tissue by means of scanning electron microscopy. The data obtained show that the nasal mucociliary function is generally reduced in children but, while in the group with poorly developed adenoids an early and progressive improvement can be observed, the children with severely hypertrophied adenoids show an impaired function up to 10 years, without age-related improvements. At almost 10 years, children with poorly developed adenoids reach normal adult clearance values. These functional data can be related to the surface characteristics of adenoid tissue. In fact, while poorly developed adenoids are characterized by a compact layer of ciliated cells, severely hypertrophied adenoids are characterized by a metaplasic epithelium, with almost complete loss of cilia. Such findings, which are probably due to the inflammatory events frequently complicating adenoid hypertrophy, could explain, together with the obstructive effects, the impairment of the nasal mucociliary clearance in childhood.

M., M., Ottaviani, F., G., P., G., A., C., Z. (1984). Adenoid hypertrophy and nasal mucociliary clearance in children. INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY, 8(1), 31-41 [10.1016/S0165-5876(84)80023-3].

Adenoid hypertrophy and nasal mucociliary clearance in children

OTTAVIANI, FABRIZIO;
1984-10-01

Abstract

he authors have studied nasal mucociliary function and adenoid surface characteristics in a group of 86 children, aged between 4 and 10 years, divided in two groups according to the presence or absence of clinical, instrumental and rontgenographic signs of nasal obstruction due to hypertrophied adenoids. Each group was divided into 3 age-related subgroups (group I: 4-5 years; group II: 6-7 years; group III: 8-10 years). A population of normal adults was chosen both for functional and ultrastructural characteristics. Nasal mucociliary clearance velocity values were evaluated by means of the saccharine method and the surface characteristics of the adenoid tissue by means of scanning electron microscopy. The data obtained show that the nasal mucociliary function is generally reduced in children but, while in the group with poorly developed adenoids an early and progressive improvement can be observed, the children with severely hypertrophied adenoids show an impaired function up to 10 years, without age-related improvements. At almost 10 years, children with poorly developed adenoids reach normal adult clearance values. These functional data can be related to the surface characteristics of adenoid tissue. In fact, while poorly developed adenoids are characterized by a compact layer of ciliated cells, severely hypertrophied adenoids are characterized by a metaplasic epithelium, with almost complete loss of cilia. Such findings, which are probably due to the inflammatory events frequently complicating adenoid hypertrophy, could explain, together with the obstructive effects, the impairment of the nasal mucociliary clearance in childhood.
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore MED/31 - Otorinolaringoiatria
English
Con Impact Factor ISI
Adenoidectomy; Nasal mucociliary clearance; Rhinomanometry
M., M., Ottaviani, F., G., P., G., A., C., Z. (1984). Adenoid hypertrophy and nasal mucociliary clearance in children. INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY, 8(1), 31-41 [10.1016/S0165-5876(84)80023-3].
M., M; Ottaviani, F; G., P; G., A; C., Z
Articolo su rivista
File in questo prodotto:
File Dimensione Formato  
Mucociliary function and nasal resistance evaluation before and after adenoidectomy.pdf

accesso aperto

Dimensione 849.83 kB
Formato Adobe PDF
849.83 kB Adobe PDF Visualizza/Apri

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/51232
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus ND
  • ???jsp.display-item.citation.isi??? ND
social impact