Single nucleotide polymorphisms (SNPs) in double-strand break repair genes may alter DNA repair capacity and, in turn, confer predisposition to leukemia. We analyzed polymorphic variants of DNA repair and detoxification genes in patients with multiple sclerosis (MS) who developed secondary acute promyelocytic leukemia (sAPL), in most cases after treatment with mitoxantrone (MTZ).

Hasan, S., Buttari, F., Ottone, T., Voso, M.t., Hohaus, S., Marasco, E., et al. (2011). Risk of acute promyelocytic leukemia in multiple sclerosis: coding variants of DNA repair genes. NEUROLOGY, 76(12), 1059-1065 [10.1212/WNL.0b013e318211c3c8].

Risk of acute promyelocytic leukemia in multiple sclerosis: coding variants of DNA repair genes

VOSO, MARIA TERESA;BERNARDI, GIORGIO;CENTONZE, DIEGO;LO COCO, FRANCESCO
2011-03-22

Abstract

Single nucleotide polymorphisms (SNPs) in double-strand break repair genes may alter DNA repair capacity and, in turn, confer predisposition to leukemia. We analyzed polymorphic variants of DNA repair and detoxification genes in patients with multiple sclerosis (MS) who developed secondary acute promyelocytic leukemia (sAPL), in most cases after treatment with mitoxantrone (MTZ).
22-mar-2011
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore MED/26 - NEUROLOGIA
English
Con Impact Factor ISI
Hasan, S., Buttari, F., Ottone, T., Voso, M.t., Hohaus, S., Marasco, E., et al. (2011). Risk of acute promyelocytic leukemia in multiple sclerosis: coding variants of DNA repair genes. NEUROLOGY, 76(12), 1059-1065 [10.1212/WNL.0b013e318211c3c8].
Hasan, S; Buttari, F; Ottone, T; Voso, Mt; Hohaus, S; Marasco, E; Mantovani, V; Garagnani, P; Sanz, M; Cicconi, L; Bernardi, G; Centonze, D; LO COCO, F
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/51205
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