Thirty-two multiple sclerosis (MS) patients, 10 males and 22 females, aged between 21 and 55, underwent pure-tone audiometry and testing of auditory brainstem response (ABR). Thirteen were classified as ‘definite’, 12 as ‘probable’ and 7 as ‘possible’, according to the McAlpine criteria. Each ear of each patient was tested monoaurally. The most common alterations were seen in the parameters of the cross-correlation between the normal template and the template of the individual MS patient. The second most altered parameters were those concerning the V wave which was absent in most cases but, when present, rarely showed latency–amplitude values falling outside the 90% confidence limit ellipses. Test–retest replicability and stimulations with increasing numbers of stimuli per second were useful in detecting intra-individual variability of waveform characteristics. When considering all the tests performed, 88% of the ‘definite’, 71% of ‘probable’ and 64% of ‘possible’ MS patients' ears showed ABR abnormalities. We stress the importance of a separate evaluation of the two ears due to the frequent unilateral alterations, and of an accurate evaluation of the ABR characteristics. We conclude that brainstem audiometry is a more reliable test for detecting demyelinating processes than is usually described in the literature.

G., P., Ottaviani, F., V., G., A., T., M., M. (1985). Auditory brainstem responses (ABR) in multiple sclerosis. SCANDINAVIAN AUDIOLOGY, 14(1), 27-34 [10.3109/01050398509045918].

Auditory brainstem responses (ABR) in multiple sclerosis

OTTAVIANI, FABRIZIO;
1985-01-01

Abstract

Thirty-two multiple sclerosis (MS) patients, 10 males and 22 females, aged between 21 and 55, underwent pure-tone audiometry and testing of auditory brainstem response (ABR). Thirteen were classified as ‘definite’, 12 as ‘probable’ and 7 as ‘possible’, according to the McAlpine criteria. Each ear of each patient was tested monoaurally. The most common alterations were seen in the parameters of the cross-correlation between the normal template and the template of the individual MS patient. The second most altered parameters were those concerning the V wave which was absent in most cases but, when present, rarely showed latency–amplitude values falling outside the 90% confidence limit ellipses. Test–retest replicability and stimulations with increasing numbers of stimuli per second were useful in detecting intra-individual variability of waveform characteristics. When considering all the tests performed, 88% of the ‘definite’, 71% of ‘probable’ and 64% of ‘possible’ MS patients' ears showed ABR abnormalities. We stress the importance of a separate evaluation of the two ears due to the frequent unilateral alterations, and of an accurate evaluation of the ABR characteristics. We conclude that brainstem audiometry is a more reliable test for detecting demyelinating processes than is usually described in the literature.
1985
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore MED/31 - OTORINOLARINGOIATRIA
Settore MED/32 - AUDIOLOGIA
Settore MED/26 - NEUROLOGIA
English
Con Impact Factor ISI
http://informahealthcare.com/doi/abs/10.3109/01050398509045918
G., P., Ottaviani, F., V., G., A., T., M., M. (1985). Auditory brainstem responses (ABR) in multiple sclerosis. SCANDINAVIAN AUDIOLOGY, 14(1), 27-34 [10.3109/01050398509045918].
G., P; Ottaviani, F; V., G; A., T; M., M
Articolo su rivista
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/50638
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus ND
  • ???jsp.display-item.citation.isi??? ND
social impact