The present study concerns the monitoring of children from the Byelorussian, Ukrainian and Russian republics exposed to the fall-out of the Chernobyl accident. Cytogenetic analyses have been performed on 41 children coming from different areas and exhibiting varying amounts of Cs-137 internal contamination, as evaluated by whole-body counter (WBC) analysis. On a total of 28670 metaphases scored, radiation-induced chromosome damage is still present, although at a very low frequency. Due to the very low fraction of dicentrics, because of the time elapsed from the accident and the relatively low doses of exposure, radiobiological dosimetry is not possible for these children. However, considering that the WBC data indicate that the children are still exposed to Cs-137 contamination, the observed occurrence of stable chromosome rearrangements and breaks may represent the persisting effect of continuous low doses of radiation. The present study also indicates that the parallel use of internal contamination dosimetry and cytogenetics could be usefully employed to monitor individual exposure to radiation and to define further management measures.

PADOVANI, L., CAPOROSSI, D., TEDESCHI, B., VERNOLE, P., NICOLETTI, B., & MAURO, F. (1993). CYTOGENETIC STUDY IN LYMPHOCYTES FROM CHILDREN EXPOSED TO IONIZING-RADIATION AFTER THE CHERNOBYL ACCIDENT. MUTATION RESEARCH, 319(1), 55-60.

CYTOGENETIC STUDY IN LYMPHOCYTES FROM CHILDREN EXPOSED TO IONIZING-RADIATION AFTER THE CHERNOBYL ACCIDENT

VERNOLE, PATRIZIA;
1993

Abstract

The present study concerns the monitoring of children from the Byelorussian, Ukrainian and Russian republics exposed to the fall-out of the Chernobyl accident. Cytogenetic analyses have been performed on 41 children coming from different areas and exhibiting varying amounts of Cs-137 internal contamination, as evaluated by whole-body counter (WBC) analysis. On a total of 28670 metaphases scored, radiation-induced chromosome damage is still present, although at a very low frequency. Due to the very low fraction of dicentrics, because of the time elapsed from the accident and the relatively low doses of exposure, radiobiological dosimetry is not possible for these children. However, considering that the WBC data indicate that the children are still exposed to Cs-137 contamination, the observed occurrence of stable chromosome rearrangements and breaks may represent the persisting effect of continuous low doses of radiation. The present study also indicates that the parallel use of internal contamination dosimetry and cytogenetics could be usefully employed to monitor individual exposure to radiation and to define further management measures.
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore BIO/13
English
Con Impact Factor ISI
CHERNOBYL; CHROMOSOME ABERRATIONS; BIOLOGICAL DOSIMETRY
PADOVANI, L., CAPOROSSI, D., TEDESCHI, B., VERNOLE, P., NICOLETTI, B., & MAURO, F. (1993). CYTOGENETIC STUDY IN LYMPHOCYTES FROM CHILDREN EXPOSED TO IONIZING-RADIATION AFTER THE CHERNOBYL ACCIDENT. MUTATION RESEARCH, 319(1), 55-60.
Padovani, L; Caporossi, D; Tedeschi, B; Vernole, P; Nicoletti, B; Mauro, F
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2108/50286
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