Background: Combined resection of solitary synchronous brain metastases and non-small-cell lung cancer has been shown to be successful. Thus, we proposed combining the surgery of solitary, extracranial metastases, and resectable lung cancer. Methods: Between March 1987 and December 1994, surgery was performed on nine patients with non-small-cell lung cancer with synchronous, solitary, extracranial, or distant metastasis: adrenal (n = 5), cutaneous (n = 2), axillary lymph node (n = 1) and kidney (n = 1). Criteria for operating on these patients included: primary tumor that was locally resectable in a radical manner, non-small-cell histology, no preoperative evidence of N2 disease, complete resection of histologically proven metastasis, and absence of other metastases found with computed tomography or bone scan. Results: Resection of the primary tumor and solitary metastases was achieved in all patients. Primary tumor was always resected by lobectomy. No mortality or major morbidity was reported. Five-year survival rate was 55.6%. Five patients who had adrenal (n = 3), or skin (n = 1), or axillary (n = 1) metastases, survived more than 5 years. All N2 patients (n = 2) died. Conclusions: The presence of solitary, distant metastasis should not be considered, per se, a factor for denying surgery for locally resectable, non-small-cell lung cancer. Unexpected, prolonged survival was demonstrated in our limited series.
Ambrogi, V., Tonini, G., & Mineo, T.C. (2001). Prolonged survival after extracranial metastasectomy from synchronous resectable lung cancer. ANNALS OF SURGICAL ONCOLOGY, 8(8), 663-666.
|Tipologia:||Articolo su rivista|
|Citazione:||Ambrogi, V., Tonini, G., & Mineo, T.C. (2001). Prolonged survival after extracranial metastasectomy from synchronous resectable lung cancer. ANNALS OF SURGICAL ONCOLOGY, 8(8), 663-666.|
|IF:||Con Impact Factor ISI|
|Settore Scientifico Disciplinare:||Settore MED/21 - Chirurgia Toracica|
|Revisione (peer review):||Sì, ma tipo non specificato|
|Stato di pubblicazione:||Pubblicato|
|Data di pubblicazione:||2001|
|Titolo:||Prolonged survival after extracranial metastasectomy from synchronous resectable lung cancer|
|Autori:||Ambrogi, V; Tonini, G; Mineo, TC|
|Appare nelle tipologie:||01 - Articolo su rivista|