Forty-one patients with low grade cervical dysplasia (CIN I) were examined using a polymerase chain reaction to establish the relationship between human papillomavirus (HPV) specific genome and progressive potential of intra-epithelial dysplasia. Thirty-one (75 per cent) of patients had human papillomavirus sequences. HPV 6/11 was detected in 19 cases, while 12 had the 'high risk' HPV type 16. Twenty-seven patients were monitored for 1 year without treatment to study the progressive potential of the cervical lesion. We observed that patients carrying HPV 16 change more readily to high grade dysplasia (CIN II or III) than patients with (or without) HPV 6/11.

Sesti, F., Romanini, C., De Santis, L., Novelli, G., Dallapiccola, B. (1995). Correlation between human papillomavirus type and progressive potential of low grade squamous intra-epithelial dysplastic lesions of the cervix (CIN I). JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 15(5), 324-327 [10.3109/01443619509030933].

Correlation between human papillomavirus type and progressive potential of low grade squamous intra-epithelial dysplastic lesions of the cervix (CIN I)

SESTI, FRANCESCO;NOVELLI, GIUSEPPE;
1995-01-01

Abstract

Forty-one patients with low grade cervical dysplasia (CIN I) were examined using a polymerase chain reaction to establish the relationship between human papillomavirus (HPV) specific genome and progressive potential of intra-epithelial dysplasia. Thirty-one (75 per cent) of patients had human papillomavirus sequences. HPV 6/11 was detected in 19 cases, while 12 had the 'high risk' HPV type 16. Twenty-seven patients were monitored for 1 year without treatment to study the progressive potential of the cervical lesion. We observed that patients carrying HPV 16 change more readily to high grade dysplasia (CIN II or III) than patients with (or without) HPV 6/11.
1995
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore MED/40 - GINECOLOGIA E OSTETRICIA
English
Con Impact Factor ISI
article; clinical article; female; human; polymerase chain reaction; priority journal; uterine cervix carcinoma in situ; uterine cervix dysplasia; virus carcinogenesis; wart virus
Sesti, F., Romanini, C., De Santis, L., Novelli, G., Dallapiccola, B. (1995). Correlation between human papillomavirus type and progressive potential of low grade squamous intra-epithelial dysplastic lesions of the cervix (CIN I). JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 15(5), 324-327 [10.3109/01443619509030933].
Sesti, F; Romanini, C; De Santis, L; Novelli, G; Dallapiccola, B
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/49910
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