Activating mutations in the K-ras oncogene mainly occur in codons 12 and 13 and may be predictive of response to drugs directly linked to the K-ras signaling pathway, such as panitumumab and cetuximab.
Palmirotta, R., Savonarola, A., Formica, V., Ludovici, G., Del Monte, G., Roselli, M., et al. (2009). A novel K-ras mutation in colorectal cancer. A case report and literature review. ANTICANCER RESEARCH, 29(8), 3369-3374.
A novel K-ras mutation in colorectal cancer. A case report and literature review
Formica, V;ROSELLI, MARIO;
2009-08-01
Abstract
Activating mutations in the K-ras oncogene mainly occur in codons 12 and 13 and may be predictive of response to drugs directly linked to the K-ras signaling pathway, such as panitumumab and cetuximab.File in questo prodotto:
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