Whether mechanical ventilation (MV) induces neurotoxicity that can trigger or accelerate chronic cognitive disorders is controversial [1, 2]. The relationship between MV and neurocognitive impairment—that persisted at hospital discharge and at 1-year follow up—was first reported in 1999 in MV-treated ARDS patients [3]. Since then, several preclinical and clinical studies have investigated the mechanisms, localization, and timing of brain damage induced by MVand possible preventive/therapeutic strategies.
Bilotta, F., Giordano, G., Sergi, P.g., Pugliese, F. (2019). Harmful effects of mechanical ventilation on neurocognitive functions. CRITICAL CARE, 23(1) [10.1186/s13054-019-2546-y].
Harmful effects of mechanical ventilation on neurocognitive functions
Bilotta F.;
2019-01-01
Abstract
Whether mechanical ventilation (MV) induces neurotoxicity that can trigger or accelerate chronic cognitive disorders is controversial [1, 2]. The relationship between MV and neurocognitive impairment—that persisted at hospital discharge and at 1-year follow up—was first reported in 1999 in MV-treated ARDS patients [3]. Since then, several preclinical and clinical studies have investigated the mechanisms, localization, and timing of brain damage induced by MVand possible preventive/therapeutic strategies.| File | Dimensione | Formato | |
|---|---|---|---|
|
Bilotta_Harmful-mechanical-ventilation_2019.pdf
non disponibili
Licenza:
Copyright dell'editore
Dimensione
309.38 kB
Formato
Adobe PDF
|
309.38 kB | Adobe PDF | Visualizza/Apri Richiedi una copia |
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
