The V118I mutation is included in the nucleoside analogue mutations (NAMs) set. It contributes to thymidine-analogue resistance and, consequently, to resistance to the whole nucleoside reverse transcriptase inhibitor (NRTI) class. We focused on the V1181 mutation in order to evaluate factors associated with its detection and its relationship with HIV progression.

Zaccarelli, M., Tozzi, V., Lorenzini, P., Forbici, F., Narciso, P., CECCHERINI SILBERSTEIN, F., et al. (2007). The V118I mutation as a marker of advanced HIV infection and disease progression. ANTIVIRAL THERAPY, 12(2), 163-168.

The V118I mutation as a marker of advanced HIV infection and disease progression

CECCHERINI SILBERSTEIN, FRANCESCA;BERTOLI, ADA;PERNO, CARLO FEDERICO;
2007-01-01

Abstract

The V118I mutation is included in the nucleoside analogue mutations (NAMs) set. It contributes to thymidine-analogue resistance and, consequently, to resistance to the whole nucleoside reverse transcriptase inhibitor (NRTI) class. We focused on the V1181 mutation in order to evaluate factors associated with its detection and its relationship with HIV progression.
2007
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore MED/07 - MICROBIOLOGIA E MICROBIOLOGIA CLINICA
English
Con Impact Factor ISI
Treatment Failure; Humans; Disease Progression; CD4 Lymphocyte Count; HIV-1; Reverse Transcriptase Inhibitors; Risk Assessment; Isoleucine; Adult; Time Factors; Male; Severity of Illness Index; Anti-HIV Agents; Prognosis; RNA, Viral; Genotype; Cross-Sectional Studies; HIV Infections; Logistic Models; Drug Resistance, Multiple, Viral; HIV Reverse Transcriptase; Follow-Up Studies; Mutation; Female; Valine; Proportional Hazards Models
Zaccarelli, M., Tozzi, V., Lorenzini, P., Forbici, F., Narciso, P., CECCHERINI SILBERSTEIN, F., et al. (2007). The V118I mutation as a marker of advanced HIV infection and disease progression. ANTIVIRAL THERAPY, 12(2), 163-168.
Zaccarelli, M; Tozzi, V; Lorenzini, P; Forbici, F; Narciso, P; CECCHERINI SILBERSTEIN, F; Trotta, M; Bertoli, A; Liuzzi, G; Marconi, P; Mosti, S; Pern...espandi
Articolo su rivista
File in questo prodotto:
Non ci sono file associati a questo prodotto.

Questo articolo è pubblicato sotto una Licenza Licenza Creative Commons Creative Commons

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/45989
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 12
  • ???jsp.display-item.citation.isi??? 12
social impact