Low p27 and high Skp2 immunoreactivity are associated with a poor prognosis and other poor prognostic features including resistant phenotypes and antiestrogen drug resistance. We investigated these proteins in two International Breast Cancer Study Group trials studying node-negative early breast cancer.

Ravaioli, A., Monti, F., Regan, M., Maffini, F., Mastropasqua, M., Spataro, V., et al. (2008). p27 and Skp2 immunoreactivity and its clinical significance with endocrine and chemo-endocrine treatments in node-negative early breast cancer. ANNALS OF ONCOLOGY, 19(4), 660-668 [10.1093/annonc/mdm547].

p27 and Skp2 immunoreactivity and its clinical significance with endocrine and chemo-endocrine treatments in node-negative early breast cancer

SPAGNOLI, LUIGI GIUSTO
2008-04-01

Abstract

Low p27 and high Skp2 immunoreactivity are associated with a poor prognosis and other poor prognostic features including resistant phenotypes and antiestrogen drug resistance. We investigated these proteins in two International Breast Cancer Study Group trials studying node-negative early breast cancer.
apr-2008
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore MED/08 - ANATOMIA PATOLOGICA
English
Proliferating Cell Nuclear Antigen; Disease-Free Survival; Antineoplastic Agents, Hormonal; Humans; Prognosis; Goserelin; Aged; Breast Neoplasms; Predictive Value of Tests; S-Phase Kinase-Associated Proteins; Cyclophosphamide; Tamoxifen; Fluorouracil; Adult; Treatment Outcome; Antineoplastic Combined Chemotherapy Protocols; Methotrexate; Middle Aged; Tumor Markers, Biological; Immunohistochemistry; Female
Ravaioli, A., Monti, F., Regan, M., Maffini, F., Mastropasqua, M., Spataro, V., et al. (2008). p27 and Skp2 immunoreactivity and its clinical significance with endocrine and chemo-endocrine treatments in node-negative early breast cancer. ANNALS OF ONCOLOGY, 19(4), 660-668 [10.1093/annonc/mdm547].
Ravaioli, A; Monti, F; Regan, M; Maffini, F; Mastropasqua, M; Spataro, V; Castiglione Gertsch, M; Panzini, I; Gianni, L; Goldhirsch, A; Coates, A; Price, K; Gusterson, B; Viale, G; Spagnoli, Lg
Articolo su rivista
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/45776
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus ND
  • ???jsp.display-item.citation.isi??? ND
social impact