In this study, 108 pediatric patients with bone marrow (BM) failure and leukemia predisposition were evaluated for presence of clonal hematopoiesis in peripheral blood (PB) and BM. Robust PB-BM concordance for mutations but decreased sensitivity in PB for chromosomal abnormalities was found.
Attardi, E., Gray, N., Lewis, S., Boals, M., Shaker, P., Kotmayer, L., et al. (2026). Utility of peripheral blood testing for detection and surveillance of clonal hematopoiesis in predisposed individuals. BLOOD, 147(8), 897-901 [10.1182/blood.2024028042].
Utility of peripheral blood testing for detection and surveillance of clonal hematopoiesis in predisposed individuals
Enrico Attardi;Maria Teresa Voso;
2026-01-01
Abstract
In this study, 108 pediatric patients with bone marrow (BM) failure and leukemia predisposition were evaluated for presence of clonal hematopoiesis in peripheral blood (PB) and BM. Robust PB-BM concordance for mutations but decreased sensitivity in PB for chromosomal abnormalities was found.File in questo prodotto:
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