We question why in their study investigating drugs for preventing postanesthetic shivering Piper et al compared placebo with dolas- etron and clonidine (1). We also wonder why they state that “a dose-response study would be scientifically important and econom- ically justified only if its side-effect profile were significantly supe- rior to that of established drugs.” We question why in their study investigating drugs for preventing postanesthetic shivering Piper et al compared placebo with dolas- etron and clonidine (1). We also wonder why they state that “a dose-response study would be scientifically important and econom- ically justified only if its side-effect profile were significantly supe- rior to that of established drugs.” We question why in their study investigating drugs for preventing postanesthetic shivering Piper et al compared placebo with dolas- etron and clonidine (1). We also wonder why they state that “a dose-response study would be scientifically important and econom- ically justified only if its side-effect profile were significantly supe- rior to that of established drugs.”
Bilotta, F., Rosa, G. (2002). PHARMACOLOGICAL PREVENTION OF POSTANESTHETIC SHIVERING. ANESTHESIA AND ANALGESIA, 95(4), 1125-1126 [10.1097/00000539-200210000-00077].
PHARMACOLOGICAL PREVENTION OF POSTANESTHETIC SHIVERING
BILOTTA F;
2002-01-01
Abstract
We question why in their study investigating drugs for preventing postanesthetic shivering Piper et al compared placebo with dolas- etron and clonidine (1). We also wonder why they state that “a dose-response study would be scientifically important and econom- ically justified only if its side-effect profile were significantly supe- rior to that of established drugs.” We question why in their study investigating drugs for preventing postanesthetic shivering Piper et al compared placebo with dolas- etron and clonidine (1). We also wonder why they state that “a dose-response study would be scientifically important and econom- ically justified only if its side-effect profile were significantly supe- rior to that of established drugs.” We question why in their study investigating drugs for preventing postanesthetic shivering Piper et al compared placebo with dolas- etron and clonidine (1). We also wonder why they state that “a dose-response study would be scientifically important and econom- ically justified only if its side-effect profile were significantly supe- rior to that of established drugs.”| File | Dimensione | Formato | |
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