A contig covering human chromosome 6p22 that consists of 134 YAC clones aligned based on the presence/absence of 52 DNA markers is presented. This contig overlaps with the 6p23 contig at its telomeric end and with the 6p21.3 contig at its centromeric end. The order of loci within the contig resolves the relative positions of several genetically mapped markers. Among the additional markers used here, there are eight novel PCR assays. The 12 known genes and anonymous ESTs located within the contig establish a first step toward a transcriptional map of this region. The instability of YAC clones observed during this work is also discussed. (C) 1996 Academic Press, Inc.
Malaspina, P., Roetto, A., Trettel, F., Iodice, C., Blasi, P., Frontali, M., et al. (1996). Construction of a YAC contig covering human chromosome 6p22. GENOMICS, 36(3), 399-407 [10.1006/geno.1996.0484].
Construction of a YAC contig covering human chromosome 6p22
MALASPINA, PATRIZIA;IODICE, CARLA;NOVELLETTO, ANDREA
1996-01-01
Abstract
A contig covering human chromosome 6p22 that consists of 134 YAC clones aligned based on the presence/absence of 52 DNA markers is presented. This contig overlaps with the 6p23 contig at its telomeric end and with the 6p21.3 contig at its centromeric end. The order of loci within the contig resolves the relative positions of several genetically mapped markers. Among the additional markers used here, there are eight novel PCR assays. The 12 known genes and anonymous ESTs located within the contig establish a first step toward a transcriptional map of this region. The instability of YAC clones observed during this work is also discussed. (C) 1996 Academic Press, Inc.| File | Dimensione | Formato | |
|---|---|---|---|
|
Malaspina_Genomics_1996.pdf
accesso aperto
Dimensione
234.18 kB
Formato
Adobe PDF
|
234.18 kB | Adobe PDF | Visualizza/Apri |
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
