Significance statementDifferently from what has been reported in most previous studies, our study has shown a low incidence of brain tumors in male children with precocious puberty, thus making the diagnosis less alarming for parents and physicians. Some criteria for a high index of suspicion of brain tumors in boys with precocious puberty have been identified. Finally, a progressive increase in the occurrence of idiopathic CPP in boys has been observed over the past two decades with a peak of new diagnoses during the pandemic lockdown, as previously reported in girls.
Amodeo, M.e., Deodati, A., Pedicelli, S., Mirra, G., Pampanini, V., Cianfarani, S. (2025). Prevalence of organic central precocious puberty in males: criteria for a high index of suspicion. ENDOCRINE CONNECTIONS, 14(2) [10.1530/EC-24-0405].
Prevalence of organic central precocious puberty in males: criteria for a high index of suspicion
Deodati A.Writing – Review & Editing
;Cianfarani S.Writing – Review & Editing
2025-01-01
Abstract
Significance statementDifferently from what has been reported in most previous studies, our study has shown a low incidence of brain tumors in male children with precocious puberty, thus making the diagnosis less alarming for parents and physicians. Some criteria for a high index of suspicion of brain tumors in boys with precocious puberty have been identified. Finally, a progressive increase in the occurrence of idiopathic CPP in boys has been observed over the past two decades with a peak of new diagnoses during the pandemic lockdown, as previously reported in girls.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.


