BACKGROUND: The juxta-anastomotic stenosis (JAS) represents the major complication of arteriovenous fistula (AVF) during the first months after the surgery and the approach to JAS can be surgical or radiological. METHODS: From 01/02/2016 to 31/12/2020, a total of 976 radiocephalic fistulas have been performed. The 15.9% of AVF was malfunctioned due to JAS. A retrospective analysis was conducted on 156 patients with JAS, in order to compare the primary outcome of surgery and percutaneous angioplasty (PTA) in JAS treatment, in the lower forearm in a follow-up of 24 months. RESULTS: Ninety patients underwent to surgery and 66 to PTA, mean age was 63.43 ± 14.54 and 65.10 ± 15.10 years, respectively. Frequencies of diabetes mellitus and arterial hypertension were similar by groups. Cardiovascular disease was present in 20% of the surgery patients and in 42.4% PTA patients (p = 0.04). The primary assisted patency was 84.4% and 71.1% in the surgery group at 12 and 24 months and 54.5% and 69.6% in the PTA group. The secondary patency at 24 months was 95.6% for surgery group and 96.9% for PTA group, without a statistical significance. During the study period, 10 AVFs (11.1%) showed a restenosis in the surgical group and 14 (21.2%) in the PTA group. CONCLUSIONS: This retrospective study suggests a higher restenosis rate after PTA than surgery. However, the statistical analysis shows that the failure rate of the two procedures is comparable. A dedicated multidisciplinary team could represent the goal for a good clinical practice in the treatment of JAS.

Dominijanni, S., Sfara, G., Tatangelo, P., Cancellieri, R., Spinelli, A., Centi, A., et al. (2025). Juxta-anastomotic stenosis in the forearm native arteriovenous fistula: Open surgery or angioplasty?. THE JOURNAL OF VASCULAR ACCESS, 26(5), 1693-1703 [10.1177/11297298241293204].

Juxta-anastomotic stenosis in the forearm native arteriovenous fistula: Open surgery or angioplasty?

Sfara, Germana;Spinelli, Alessio;Marrone, Giulia;Noce, Annalisa;
2025-09-01

Abstract

BACKGROUND: The juxta-anastomotic stenosis (JAS) represents the major complication of arteriovenous fistula (AVF) during the first months after the surgery and the approach to JAS can be surgical or radiological. METHODS: From 01/02/2016 to 31/12/2020, a total of 976 radiocephalic fistulas have been performed. The 15.9% of AVF was malfunctioned due to JAS. A retrospective analysis was conducted on 156 patients with JAS, in order to compare the primary outcome of surgery and percutaneous angioplasty (PTA) in JAS treatment, in the lower forearm in a follow-up of 24 months. RESULTS: Ninety patients underwent to surgery and 66 to PTA, mean age was 63.43 ± 14.54 and 65.10 ± 15.10 years, respectively. Frequencies of diabetes mellitus and arterial hypertension were similar by groups. Cardiovascular disease was present in 20% of the surgery patients and in 42.4% PTA patients (p = 0.04). The primary assisted patency was 84.4% and 71.1% in the surgery group at 12 and 24 months and 54.5% and 69.6% in the PTA group. The secondary patency at 24 months was 95.6% for surgery group and 96.9% for PTA group, without a statistical significance. During the study period, 10 AVFs (11.1%) showed a restenosis in the surgical group and 14 (21.2%) in the PTA group. CONCLUSIONS: This retrospective study suggests a higher restenosis rate after PTA than surgery. However, the statistical analysis shows that the failure rate of the two procedures is comparable. A dedicated multidisciplinary team could represent the goal for a good clinical practice in the treatment of JAS.
set-2025
Pubblicato
Rilevanza internazionale
Articolo
Esperti non anonimi
Settore MEDS-08/B - Nefrologia
English
Hemodialysis
intimal hyperplasia
juxta-anastomotic stenosis
multidisciplinary team
percutaneous transluminal angioplasty
Dominijanni, S., Sfara, G., Tatangelo, P., Cancellieri, R., Spinelli, A., Centi, A., et al. (2025). Juxta-anastomotic stenosis in the forearm native arteriovenous fistula: Open surgery or angioplasty?. THE JOURNAL OF VASCULAR ACCESS, 26(5), 1693-1703 [10.1177/11297298241293204].
Dominijanni, S; Sfara, G; Tatangelo, P; Cancellieri, R; Spinelli, A; Centi, A; Mariani, I; Ammirati, Lm; Marrone, G; Mudoni, A; Noce, A; Palumbo, R...espandi
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/445023
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