Hybrid Nanozyme System: Gold-Decorated Nanodiamonds for Advanced Electrochemical Sensing

The text discusses the use of nanozymes, specifically gold nanoparticles (AuNPs), for electrochemical sensing owing to their benefits over natural enzymes in stability, reusability, and cost. Traditional synthesis methods for AuNPs can hinder efficiency, leading to the development of a new synthesis strategy utilizing nanodiamonds (NDs) as a support. NDs provide high surface area and chemical stability, resulting in ND-AuNPs hybrids exhibiting enhanced catalytic activity and stability. Additionally, a second hybrid using sp2nanocarbons derived from cellulose-based waste was created. When applied to screen-printed electrodes, both hybrid systems demonstrate improved electron transfer and heightened sensitivity, validating their potential integration into electrochemical sensors for detecting hydrogen peroxide. This study emphasizes the potential of using nanodiamonds and sustainable materials to advance nanozyme-based, enzyme-free electrochemical sensors for environmental and biomedical applications.