Six new Y-specific probes have been isolated and are reported. Along with another six already described they have been used in a systematic search for male specific RFLPs. An overall number of 46515 nucleotides have been screened with 12 enzymes and no polymorphic pattern observed. Our data reveal a greatly reduced level of polymorphism compared with other chromosomes.

Malaspina, P., Persichetti, F., Novelletto, A., Iodice, C., Terrenato, L., Wolfe, J., et al. (1990). The human Y chromosome shows a low level of DNA polymorphism. ANNALS OF HUMAN GENETICS, 54(4), 297-305 [10.1111/j.1469-1809.1990.tb00385.x].

The human Y chromosome shows a low level of DNA polymorphism

MALASPINA, PATRIZIA;NOVELLETTO, ANDREA;IODICE, CARLA;TERRENATO, LUCIANO;
1990-01-01

Abstract

Six new Y-specific probes have been isolated and are reported. Along with another six already described they have been used in a systematic search for male specific RFLPs. An overall number of 46515 nucleotides have been screened with 12 enzymes and no polymorphic pattern observed. Our data reveal a greatly reduced level of polymorphism compared with other chromosomes.
1990
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore BIO/18 - GENETICA
English
Con Impact Factor ISI
article; controlled study; dna polymorphism; dna probe; human; in situ hybridization; male; normal human; priority journal; Y chromosome; Animal; Chromosome Banding; DNA Probes; Female; Human; Hybrid Cells; Male; Mice; Polymorphism, Restriction Fragment Length; Restriction Mapping; Support, Non-U.S. Gov't; Y Chromosome
Malaspina, P., Persichetti, F., Novelletto, A., Iodice, C., Terrenato, L., Wolfe, J., et al. (1990). The human Y chromosome shows a low level of DNA polymorphism. ANNALS OF HUMAN GENETICS, 54(4), 297-305 [10.1111/j.1469-1809.1990.tb00385.x].
Malaspina, P; Persichetti, F; Novelletto, A; Iodice, C; Terrenato, L; Wolfe, J; Ferraro, M; Prantera, G
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/44465
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