Erythrocyte micronucleus frequencies in wild fish from two riverine environments and in fish reproduced and reared under controlled conditions (control group) were compared, with the aim to evaluate the suitability of the MN test for the in situ detection of mutagens in freshwaters. Fish were caught in different months in two rivers of central ItaIy which have different pollution levels. As indicator species, the barbel (Barbus plebejus) was chosen because of its ecological significance. Blood samplings wen performed on wild fish immediately after capture and repeated at different time intervals on the same individuals, which were maintained in controlled conditions after capture. A total of 10,000 erythrocytes per specimen were scored. No significant differences in micronucleus frequencies were observed between the control group and fish from the unpolluted river (Mignone). A significantly higher frequency of micronuclei was observed in fish caught in the polluted river (Tibet), in comparison to both the controls and the Mignone river fish. No significant seasonal differences were observed. Barbels examined 50 and 100 days after capture presented a remarkable decrease in micronucleus frequency in comparison with the frequency observed in barbels at capture. The micronucleus test in fish erythrocytes was shown to be a sensitive bioassay for detecting mutagenic pollution in fresh water environments.

Minissi, S., Ciccotti, E., Rizzoni, M. (1996). Micronucleus test in erythrocytes of Barbus plebejus (Teleostei, Pisces) from two natural environments: A bioassay for the in situ detection of mutagens in freshwater. MUTATION RESEARCH. GENETIC TOXICOLOGY TESTING, 367(4), 245-251 [10.1016/S0165-1218(96)90084-1].

Micronucleus test in erythrocytes of Barbus plebejus (Teleostei, Pisces) from two natural environments: A bioassay for the in situ detection of mutagens in freshwater

CICCOTTI, ELEONORA;RIZZONI, MARCO
1996-01-01

Abstract

Erythrocyte micronucleus frequencies in wild fish from two riverine environments and in fish reproduced and reared under controlled conditions (control group) were compared, with the aim to evaluate the suitability of the MN test for the in situ detection of mutagens in freshwaters. Fish were caught in different months in two rivers of central ItaIy which have different pollution levels. As indicator species, the barbel (Barbus plebejus) was chosen because of its ecological significance. Blood samplings wen performed on wild fish immediately after capture and repeated at different time intervals on the same individuals, which were maintained in controlled conditions after capture. A total of 10,000 erythrocytes per specimen were scored. No significant differences in micronucleus frequencies were observed between the control group and fish from the unpolluted river (Mignone). A significantly higher frequency of micronuclei was observed in fish caught in the polluted river (Tibet), in comparison to both the controls and the Mignone river fish. No significant seasonal differences were observed. Barbels examined 50 and 100 days after capture presented a remarkable decrease in micronucleus frequency in comparison with the frequency observed in barbels at capture. The micronucleus test in fish erythrocytes was shown to be a sensitive bioassay for detecting mutagenic pollution in fresh water environments.
1996
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore BIO/07 - ECOLOGIA
English
Con Impact Factor ISI
Bioassay; Fish; Micronucleus; Mutagenic pollution
Scopus Indexed keywords EMTREE drug terms: fresh water, mutagenic agent, river water EMTREE medical terms: animal experiment, article, bioassaycontrolled study, erythrocyte fish italy, micronucleus, micronucleus test, mutagen testing, mutagenicity non human, priority journal, teleost, water pollution, water pollution indicator MeSH: Animals, Erythrocytes, Fishes, Fresh Water, Italy, Micronuclei, Chromosome-Defective Micronucleus,, Tests Mutagens, Seasons, Water Pollutants, Chemical
WOS KeyWords Plus:ETHYL METHANESULFONATE; EASTERN MUDMINNOW; UMBRA-PYGMAEA; RIVER WATER; FISH; INDUCTION; GENOTOXICITY
Metrics in Scopus 99 Citations 96th Percentile 1.34 Field-Weighted Citation Impact 14 Mendeley Readers 91st Percentile WOS All Times Cited Counts 97 in All Databases 92 in Web of Science Core Collection 89 in BIOSIS Citation Index 1 in Chinese Science Citation Database JOURNAL INFORMATION Mutation Research Journal Metrics CiteScore: 2.25 More about CiteScore Impact Factor: 2.133 5-Year Impact Factor: 2.528 Source Normalized Impact per Paper (SNIP): 0.937 SCImago Journal Rank (SJR): 0.924 ℹ
Minissi, S., Ciccotti, E., Rizzoni, M. (1996). Micronucleus test in erythrocytes of Barbus plebejus (Teleostei, Pisces) from two natural environments: A bioassay for the in situ detection of mutagens in freshwater. MUTATION RESEARCH. GENETIC TOXICOLOGY TESTING, 367(4), 245-251 [10.1016/S0165-1218(96)90084-1].
Minissi, S; Ciccotti, E; Rizzoni, M
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/43764
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