Pulmonary carcinoids are rare malignant neoplasms, accounting for 2-5% of all lung tumors, with an approximate annual incidence of 2.3-2.8 cases per million of the population. We relate our experience of 54 patients (21 male, 33 female, mean age 53+/-15 years) treated between July 1986 and April 2006. All the patients underwent preoperative fibrobronchoscopy: preoperative diagnosis was made in 28 patients (52%). Surgical treatment consisted of: 31 standard lobectomies, 6 pneumonectomies, 5 bilobectomies, 2 sleeve lobectomies, 2 anatomic segmentectomies, 6 wedge resections; two patients were managed with sleeve bronchial procedure of the left main bronchus without lung resection. Fifty-four patients were followed with a mean time of observation of 67 months: 6 (11%) deaths occurred, at a mean period of 49 months after surgery; there were no postoperative deaths. Overall, 5-year survival was 91%, 10 years 83%: 5-year survival was 91% for typical carcoinoids (TC) vs. 88% for atypical (AC), 10 years 91% for TC and 44% for AC (significant value, P=0.0487). Carcinoid tumors are a distinct group of neuroendocrine tumors with a good prognosis in most cases. Surgery currently represents the best treatment with good results at mid- and long-term survival, according to an acceptable risk.

Bini, A., Brandolini, J., Cassanelli, N., Davoli, F., Dolci, G., Sellitri, F., et al. (2008). Typical and atypical pulmonary carcinoids: our institutional experience. INTERACTIVE CARDIOVASCULAR AND THORACIC SURGERY, 7(3), 415-418 [10.1510/icvts.2007.173328].

Typical and atypical pulmonary carcinoids: our institutional experience

SELLITRI, FRANCESCO;
2008-05-01

Abstract

Pulmonary carcinoids are rare malignant neoplasms, accounting for 2-5% of all lung tumors, with an approximate annual incidence of 2.3-2.8 cases per million of the population. We relate our experience of 54 patients (21 male, 33 female, mean age 53+/-15 years) treated between July 1986 and April 2006. All the patients underwent preoperative fibrobronchoscopy: preoperative diagnosis was made in 28 patients (52%). Surgical treatment consisted of: 31 standard lobectomies, 6 pneumonectomies, 5 bilobectomies, 2 sleeve lobectomies, 2 anatomic segmentectomies, 6 wedge resections; two patients were managed with sleeve bronchial procedure of the left main bronchus without lung resection. Fifty-four patients were followed with a mean time of observation of 67 months: 6 (11%) deaths occurred, at a mean period of 49 months after surgery; there were no postoperative deaths. Overall, 5-year survival was 91%, 10 years 83%: 5-year survival was 91% for typical carcoinoids (TC) vs. 88% for atypical (AC), 10 years 91% for TC and 44% for AC (significant value, P=0.0487). Carcinoid tumors are a distinct group of neuroendocrine tumors with a good prognosis in most cases. Surgery currently represents the best treatment with good results at mid- and long-term survival, according to an acceptable risk.
mag-2008
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore MED/21 - CHIRURGIA TORACICA
English
Senza Impact Factor ISI
Neoplasm Staging; Humans; Aged; Bronchial Neoplasms; Kaplan-Meier Estimate; Pneumonectomy; Bronchoscopy; Fiber Optic Technology; Adult; Treatment Outcome; Carcinoid Tumor; Follow-Up Studies; Middle Aged; Time Factors; Female; Male
Bini, A., Brandolini, J., Cassanelli, N., Davoli, F., Dolci, G., Sellitri, F., et al. (2008). Typical and atypical pulmonary carcinoids: our institutional experience. INTERACTIVE CARDIOVASCULAR AND THORACIC SURGERY, 7(3), 415-418 [10.1510/icvts.2007.173328].
Bini, A; Brandolini, J; Cassanelli, N; Davoli, F; Dolci, G; Sellitri, F; Stella, F
Articolo su rivista
File in questo prodotto:
File Dimensione Formato  
4.pdf

accesso aperto

Dimensione 187.13 kB
Formato Adobe PDF
187.13 kB Adobe PDF Visualizza/Apri

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/43688
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 44
  • ???jsp.display-item.citation.isi??? ND
social impact