Innovative hydrogels obtained by physical and chemical crosslinking of deacylated Gellan gum have been characterized in terms of water uptake, rheological properties and compressibility, and the behaviour of the tested materials, according to the type of the obtained network, is thoroughly discussed. The release from the various gels of loaded model molecules of different steric hindrance was also investigated and the trend of the release profiles has been related to the structures proposed for the physical and the chemical hydrogel.

Matricardi, P., Claudia, C., Roberto, R., Alhaique, F., Coviello, T. (2009). Preparation and Characterization of Novel Gellan Gum Hydrogels Suitable for Modified Drug Release. MOLECULES, 14(9), 3376-3391 [10.3390/molecules14093376].

Preparation and Characterization of Novel Gellan Gum Hydrogels Suitable for Modified Drug Release

MATRICARDI, PIETRO;ALHAIQUE, Franco;
2009-01-01

Abstract

Innovative hydrogels obtained by physical and chemical crosslinking of deacylated Gellan gum have been characterized in terms of water uptake, rheological properties and compressibility, and the behaviour of the tested materials, according to the type of the obtained network, is thoroughly discussed. The release from the various gels of loaded model molecules of different steric hindrance was also investigated and the trend of the release profiles has been related to the structures proposed for the physical and the chemical hydrogel.
2009
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore CHEM-08/A - Tecnologia, socioeconomia e normativa dei medicinali e dei prodotti per il benessere e per la salute
English
Con Impact Factor ISI
gellan
hydrogels
modified drug release
rheology
texture analysis
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Matricardi, P., Claudia, C., Roberto, R., Alhaique, F., Coviello, T. (2009). Preparation and Characterization of Novel Gellan Gum Hydrogels Suitable for Modified Drug Release. MOLECULES, 14(9), 3376-3391 [10.3390/molecules14093376].
Matricardi, P; Claudia, C; Roberto, R; Alhaique, F; Coviello, T
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/430652
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