Streptococcus pneumoniae pathologies represent a health problem of primary importance worldwide in terms of morbidity, mortality, and costs. S. pneumoniae is the main aetiological agent of bacterial pneumonia, and is frequently involved in bacterial meningitis, chronic obstructive pulmonary disease (COPD) exacerbations and upper airway pathologies. The high incidence, the level of morbidity and mortality due to pneumococcal pathology despite of adequate therapy, and the emergence of antibiotic-resistant strains emphasize the importance of an effective vaccine strategy against this bacterium. The present review proposes an analysis of current vaccine strategies and their efficacy, with particular stress on their effectiveness in preventing pneumonia. © 2008 Elsevier Ltd. All rights reserved.

Braido F., B.M. (2008). The role of Pneumococcal vaccine. PULMONARY PHARMACOLOGY & THERAPEUTICS, 21(4), 608-615 [10.1016/j.pupt.2008.04.001].

The role of Pneumococcal vaccine

CAZZOLA, MARIO;
2008

Abstract

Streptococcus pneumoniae pathologies represent a health problem of primary importance worldwide in terms of morbidity, mortality, and costs. S. pneumoniae is the main aetiological agent of bacterial pneumonia, and is frequently involved in bacterial meningitis, chronic obstructive pulmonary disease (COPD) exacerbations and upper airway pathologies. The high incidence, the level of morbidity and mortality due to pneumococcal pathology despite of adequate therapy, and the emergence of antibiotic-resistant strains emphasize the importance of an effective vaccine strategy against this bacterium. The present review proposes an analysis of current vaccine strategies and their efficacy, with particular stress on their effectiveness in preventing pneumonia. © 2008 Elsevier Ltd. All rights reserved.
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore MED/10 - Malattie dell'Apparato Respiratorio
eng
Con Impact Factor ISI
Airway pathologies; COPD; Pneumonia; Streptococcus pneumoniae; Vaccine
Braido F., B.M. (2008). The role of Pneumococcal vaccine. PULMONARY PHARMACOLOGY & THERAPEUTICS, 21(4), 608-615 [10.1016/j.pupt.2008.04.001].
Braido, F; Bellotti, M; De Maria, A; Cazzola, M; Canonica, Gw
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2108/42145
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