Prostatic stromal sarcoma (PSS) is a rare tumor that normally occurs in adult age. Its management relies mainly on surgery. We report the first case of PSS occurring in an adolescent. There was evidence of a good response to chemotherapy including ifosfamide, doxorubicin, vincristine and actinomycin-D, although the final outcome was dismal. A review of the English literature revealed 14 additional patients with PSS treated with chemotherapy: tumor shrinkage was reported in 4 of the 6 evaluable patients. Patients with PSS may benefit from the use of chemotherapy in combination with early aggressive local treatment.
Cavaliere, E., Alaggio, R., Castagnetti, M., Scarzello, G., Bisogno, G. (2014). Prostatic stromal sarcoma in an adolescent: the role of chemotherapy. RARE TUMORS, Volume 6, Issue 4, 23 October 2014, Article number 5607, Pages 146-149(4), 146-149 [10.4081/rt.2014.5607].
Prostatic stromal sarcoma in an adolescent: the role of chemotherapy
Castagnetti M;
2014-01-01
Abstract
Prostatic stromal sarcoma (PSS) is a rare tumor that normally occurs in adult age. Its management relies mainly on surgery. We report the first case of PSS occurring in an adolescent. There was evidence of a good response to chemotherapy including ifosfamide, doxorubicin, vincristine and actinomycin-D, although the final outcome was dismal. A review of the English literature revealed 14 additional patients with PSS treated with chemotherapy: tumor shrinkage was reported in 4 of the 6 evaluable patients. Patients with PSS may benefit from the use of chemotherapy in combination with early aggressive local treatment.| File | Dimensione | Formato | |
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