The authors describe two cases of sarcomas of the skull following cranial irradiation in patients treated for other neoplasms, acute lymphatic leukemia, and astrocytoma, respectively. The patients (one man and one woman; mean age 24.5 years) developed sarcomas within the irradiated field after a mean latency period of 11.5 years. Histologically, the tumor proved to be a fibrosarcoma. Despite aggressive surgery and other therapy, the survival of the patients was short (10 and 8 months, respectively). The pathological and clinical aspects of this unusual complication are analyzed with reference to 41 cases taken from the world literature.

Salvati, M., Cervoni, L., Raguso, M., Gagliardi, M. (1997). Radiation-induced sarcoma of the skull: Report of two cases. ITALIAN JOURNAL OF NEUROLOGICAL SCIENCES, 18(2), 101-104 [10.1007/BF01999570].

Radiation-induced sarcoma of the skull: Report of two cases

Salvati, M.;Gagliardi, M.
1997-01-01

Abstract

The authors describe two cases of sarcomas of the skull following cranial irradiation in patients treated for other neoplasms, acute lymphatic leukemia, and astrocytoma, respectively. The patients (one man and one woman; mean age 24.5 years) developed sarcomas within the irradiated field after a mean latency period of 11.5 years. Histologically, the tumor proved to be a fibrosarcoma. Despite aggressive surgery and other therapy, the survival of the patients was short (10 and 8 months, respectively). The pathological and clinical aspects of this unusual complication are analyzed with reference to 41 cases taken from the world literature.
1997
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MEDS-15/A - Neurochirurgia
English
Radio-induced tumors
Radiotherapy
Sarcoma
Salvati, M., Cervoni, L., Raguso, M., Gagliardi, M. (1997). Radiation-induced sarcoma of the skull: Report of two cases. ITALIAN JOURNAL OF NEUROLOGICAL SCIENCES, 18(2), 101-104 [10.1007/BF01999570].
Salvati, M; Cervoni, L; Raguso, M; Gagliardi, M
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/412911
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