An increased number of HIV-infected patients have experienced most or all available antiretroviral drugs. or these patients, building a salvage or rescue regimen is difficult. Resistance to highly active antiretroviral therapy (HAART) makes the clinical decision process complex. However, growing understanding of HIV dynamics and resistance patterns to HAART may help physicians make more rational decisions when planning treatments in highly experienced patients. Viral resistance mutations may have favourable effects in salvage treatment by reducing viral fitness and pathogenicity. Similarly, interactions between mutations may possibly increase susceptibility to other antiretroviral drugs.

Geretti, A.m. (2002). A virological perspective on resistance in highly treatment-experienced patients. JOURNAL OF HIV THERAPY, 7(4), 97-101.

A virological perspective on resistance in highly treatment-experienced patients

Geretti A. M.
2002-01-01

Abstract

An increased number of HIV-infected patients have experienced most or all available antiretroviral drugs. or these patients, building a salvage or rescue regimen is difficult. Resistance to highly active antiretroviral therapy (HAART) makes the clinical decision process complex. However, growing understanding of HIV dynamics and resistance patterns to HAART may help physicians make more rational decisions when planning treatments in highly experienced patients. Viral resistance mutations may have favourable effects in salvage treatment by reducing viral fitness and pathogenicity. Similarly, interactions between mutations may possibly increase susceptibility to other antiretroviral drugs.
2002
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MEDS-10/B - Malattie infettive
English
Geretti, A.m. (2002). A virological perspective on resistance in highly treatment-experienced patients. JOURNAL OF HIV THERAPY, 7(4), 97-101.
Geretti, Am
Articolo su rivista
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/409988
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