HLA loss represents the result of immune forces shaping bone marrow clonal dynamics in immune aplastic anaemia. Human leukocyte antigen (HLA)-deficient clones may rescue haematopoiesis by evading immune attacks, potentially guiding treatment strategies. Commentary on: Zaimoku et al. Haematopoietic regeneration by HLA-A*0206-deficient clones in severe aplastic anaemia without definitive immunosuppressive treatment. Br J Haematol 2024; 205:1995-1999.
Gurnari, C., Lima, A., Pagliuca, S. (2024). HLA-lacking clones in aplastic anaemia: Adaptive or maladaptive?. BRITISH JOURNAL OF HAEMATOLOGY, 205(5), 1681-1682 [10.1111/bjh.19731].
HLA-lacking clones in aplastic anaemia: Adaptive or maladaptive?
Gurnari C.Writing – Original Draft Preparation
;
2024-01-01
Abstract
HLA loss represents the result of immune forces shaping bone marrow clonal dynamics in immune aplastic anaemia. Human leukocyte antigen (HLA)-deficient clones may rescue haematopoiesis by evading immune attacks, potentially guiding treatment strategies. Commentary on: Zaimoku et al. Haematopoietic regeneration by HLA-A*0206-deficient clones in severe aplastic anaemia without definitive immunosuppressive treatment. Br J Haematol 2024; 205:1995-1999.| File | Dimensione | Formato | |
|---|---|---|---|
|
HLA-lacking clone.pdf
accesso aperto
Tipologia:
Versione Editoriale (PDF)
Licenza:
Creative commons
Dimensione
159.13 kB
Formato
Adobe PDF
|
159.13 kB | Adobe PDF | Visualizza/Apri |
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
