Glycated hemoglobin (HbA1c) provides a useful estimate of mean glycemia in patients with diabetes and is directly related to risks for diabetes complications. The aim of this study is to compare a capillary electrophoresis method and two high-performance liquid chromatography (HPLC) cation-exchange analyzers (Variant II (Bio-Rad Laboratories, Inc., Hercules, CA) and G8 (Tosoh Biosciences, San Francisco, CA)) to identify the most reliable method in Hb variants' presence.
Dessi', M., Pieri, M., Pignalosa, S., Martino, F., Zenobi, R. (2015). Performances of capillary electrophoresis and HPLC methods in HbA1c determination: Diagnostic accuracy in HbS and HbD-Iran variants' presence. JOURNAL OF CLINICAL LABORATORY ANALYSIS, 29(1), 57-60 [10.1002/jcla.21728].
Performances of capillary electrophoresis and HPLC methods in HbA1c determination: Diagnostic accuracy in HbS and HbD-Iran variants' presence
DESSI', MARIARITA;PIERI, MASSIMO;ZENOBI, ROSSELLA
2015-01-01
Abstract
Glycated hemoglobin (HbA1c) provides a useful estimate of mean glycemia in patients with diabetes and is directly related to risks for diabetes complications. The aim of this study is to compare a capillary electrophoresis method and two high-performance liquid chromatography (HPLC) cation-exchange analyzers (Variant II (Bio-Rad Laboratories, Inc., Hercules, CA) and G8 (Tosoh Biosciences, San Francisco, CA)) to identify the most reliable method in Hb variants' presence.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
