Emoglobina glicata in base al genere: possibili valori di riferimento.

Background.: Diabetes has become “a global epidemic”, as reported the World Health Organization (WHO). Glycated hemoglobin (HbA1c), considered one of the methods of choice for the diagnosis of diabetes, reflects glicemia over the preceding 6–8 weeks. Elevated HbA1c values are associated with the development of long-term complications in both type 1 and type 2 diabetes. According to the WHO guidelines, HbA1c ≥ 48 mmol/mol (6.5%) can be used to diagnose diabetes in most situations; currently this recommendation is not different in gender. The aim of this study is to analyze HbA1c values to verify if there are significant differences related to gender. Methods.: 515 blood samples obtained from a cohort of healthy White/Caucasian donors of “San Filippo Neri” Hospital and “Tor Vergata” University Hospital were analyzed by Capillarys 2-FP (Sebia, Lisses, France). Results.: The data showed a mean of 32.2±4.0 mmol/mol for males; 30±3.8 mmol/mol for females (p<0.001). Conclusions.: A diverse threshold should be used for male and female, whether the difference of “media” will be confirmed, extending the analysis to a wider population.