Expression of T cell specific zeta-associated protein 70 (ZAP-70) by B-cell chronic lymphocytic leukemia (B-CLL) cells, as investigated by flow cytometry, has both prognostic relevance and predictive power as surrogate for immunoglobulin heavy chain variable region (IgV(H)) mutations, although a standardization of the cytometric protocol is still lacking.

Zucchetto, A., Bomben, R., Bo, M., Nanni, P., Bulian, P., Rossi, F., et al. (2006). ZAP-70 expression in B-cell chronic lymphocytic leukemia: evaluation by external (isotypic) or internal (T/NK cells) controls and correlation with IgV(H) mutations. CYTOMETRY. PART B, CLINICAL CYTOMETRY, 70(4), 284-292 [10.1002/cyto.b.20127].

ZAP-70 expression in B-cell chronic lymphocytic leukemia: evaluation by external (isotypic) or internal (T/NK cells) controls and correlation with IgV(H) mutations

DEL PRINCIPE, MARIA ILARIA;DEL POETA, GIOVANNI;
2006-07-15

Abstract

Expression of T cell specific zeta-associated protein 70 (ZAP-70) by B-cell chronic lymphocytic leukemia (B-CLL) cells, as investigated by flow cytometry, has both prognostic relevance and predictive power as surrogate for immunoglobulin heavy chain variable region (IgV(H)) mutations, although a standardization of the cytometric protocol is still lacking.
15-lug-2006
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore MED/15 - MALATTIE DEL SANGUE
English
Con Impact Factor ISI
Reproducibility of Results; Humans; Aged; Calibration; Aged, 80 and over; Leukemia, Lymphocytic, Chronic, B-Cell; Killer Cells, Natural; Adult; Immunoglobulin Variable Region; Flow Cytometry; Middle Aged; Immunoglobulin Heavy Chains; Tumor Markers, Biological; Mutation; Female; Male; ZAP-70 Protein-Tyrosine Kinase; T-Lymphocytes
Zucchetto, A., Bomben, R., Bo, M., Nanni, P., Bulian, P., Rossi, F., et al. (2006). ZAP-70 expression in B-cell chronic lymphocytic leukemia: evaluation by external (isotypic) or internal (T/NK cells) controls and correlation with IgV(H) mutations. CYTOMETRY. PART B, CLINICAL CYTOMETRY, 70(4), 284-292 [10.1002/cyto.b.20127].
Zucchetto, A; Bomben, R; Bo, M; Nanni, P; Bulian, P; Rossi, F; DEL PRINCIPE, Mi; Santini, S; DEL POETA, G; Degan, M; Gattei, V
Articolo su rivista
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/40664
Citazioni
  • ???jsp.display-item.citation.pmc??? 6
  • Scopus 39
  • ???jsp.display-item.citation.isi??? 36
social impact