Hypersusceptibility to nonnucleoside reverse-transcriptase inhibitors (NNRTIs) was described in association with reverse-transcriptase (RT) mutations conferring resistance to nucleoside reverse-transcriptase inhibitors (NRTIs). We evaluated the effect of RT mutations associated with hypersusceptibility to NNRTIs on the response to efavirenz-based therapy.

Tozzi, V., Zaccarelli, M., Narciso, P., Trotta, M., CECCHERINI SILBERSTEIN, F., De Longis, P., et al. (2004). Mutations in HIV-1 reverse transcriptase potentially associated with hypersusceptibility to nonnucleoside reverse-transcriptase inhibitors: effect on response to efavirenz-based therapy in an urban observational cohort. THE JOURNAL OF INFECTIOUS DISEASES, 189(9), 1688-1695 [10.1086/382960].

Mutations in HIV-1 reverse transcriptase potentially associated with hypersusceptibility to nonnucleoside reverse-transcriptase inhibitors: effect on response to efavirenz-based therapy in an urban observational cohort

CECCHERINI SILBERSTEIN, FRANCESCA;PERNO, CARLO FEDERICO
2004-05-01

Abstract

Hypersusceptibility to nonnucleoside reverse-transcriptase inhibitors (NNRTIs) was described in association with reverse-transcriptase (RT) mutations conferring resistance to nucleoside reverse-transcriptase inhibitors (NRTIs). We evaluated the effect of RT mutations associated with hypersusceptibility to NNRTIs on the response to efavirenz-based therapy.
1-mag-2004
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore MED/07 - MICROBIOLOGIA E MICROBIOLOGIA CLINICA
English
Con Impact Factor ISI
Anti-HIV Agents; Humans; CD4 Lymphocyte Count; HIV-1; Reverse Transcriptase Inhibitors; Protease Inhibitors; Viral Load; Drug Therapy, Combination; Drug Resistance, Viral; HIV Infections; Adult; Cohort Studies; Treatment Outcome; Oxazines; HIV Reverse Transcriptase; Urban Population; Microbial Sensitivity Tests; Mutation; Male; Benzoxazines; Female
Tozzi, V., Zaccarelli, M., Narciso, P., Trotta, M., CECCHERINI SILBERSTEIN, F., De Longis, P., et al. (2004). Mutations in HIV-1 reverse transcriptase potentially associated with hypersusceptibility to nonnucleoside reverse-transcriptase inhibitors: effect on response to efavirenz-based therapy in an urban observational cohort. THE JOURNAL OF INFECTIOUS DISEASES, 189(9), 1688-1695 [10.1086/382960].
Tozzi, V; Zaccarelli, M; Narciso, P; Trotta, M; CECCHERINI SILBERSTEIN, F; De Longis, P; D'Offizi, G; Forbici, F; D'Arrigo, R; Boumis, E; Bellagamba, ...espandi
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/40660
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