Multiparametric flow cytometry has become an indispensable but complex tool for the diagnosis of acute leukemias. Interpretation of immunophenotypic data within a six-parameter analytical space relies on the standardization and validation of the instrument, the reagents, and the procedure. To address whether or not residual normal lymphocytes, usually present within leukemic samples, can serve as internal quality control for fluorescence intensity, 116 leukemic and 35 normal samples were analyzed.

Ratei, R., Karawajew, L., Lacombe, F., Jagoda, K., DEL POETA, G., Kraan, J., et al. (2006). Normal lymphocytes from leukemic samples as an internal quality control for fluorescence intensity in immunophenotyping of acute leukemias. CYTOMETRY. PART B, CLINICAL CYTOMETRY, 70(1), 1-9 [10.1002/cyto.b.20075].

Normal lymphocytes from leukemic samples as an internal quality control for fluorescence intensity in immunophenotyping of acute leukemias

DEL POETA, GIOVANNI;
2006-01-01

Abstract

Multiparametric flow cytometry has become an indispensable but complex tool for the diagnosis of acute leukemias. Interpretation of immunophenotypic data within a six-parameter analytical space relies on the standardization and validation of the instrument, the reagents, and the procedure. To address whether or not residual normal lymphocytes, usually present within leukemic samples, can serve as internal quality control for fluorescence intensity, 116 leukemic and 35 normal samples were analyzed.
gen-2006
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore MED/15 - MALATTIE DEL SANGUE
English
Con Impact Factor ISI
Acute Disease; Leukemia; Fluorescence; Humans; Reference Standards; Case-Control Studies; Flow Cytometry; Lymphocytes; Quality Control; Immunophenotyping
Ratei, R., Karawajew, L., Lacombe, F., Jagoda, K., DEL POETA, G., Kraan, J., et al. (2006). Normal lymphocytes from leukemic samples as an internal quality control for fluorescence intensity in immunophenotyping of acute leukemias. CYTOMETRY. PART B, CLINICAL CYTOMETRY, 70(1), 1-9 [10.1002/cyto.b.20075].
Ratei, R; Karawajew, L; Lacombe, F; Jagoda, K; DEL POETA, G; Kraan, J; De Santiago, M; Kappelmayer, J; Björklund, E; Ludwig, W; Gratama, J; Orfao, A
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/40657
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