equine gastric ulcer syndrome (EGUS) is a worldwide disease, found especially in racehorses, although it can affect different categories of animals with difference in prevalence. recently, two different diseases have been recognized, the first affecting the squamous mucosa (equine squamous gastric disease, ESGD) and the other the glandular mucosa (equine glandular gastric disease, EGGD), with different pathophysiology, risk factors and management. to date, the main strategy for the treatment involves acid-suppressive therapy with omeprazole, often associated with sucralfate; yet the total safety and absence of side effects of this treatment have recently been questioned. recently, an increasing number of studies have been investigating the use of complementary feeds to manage of these health issues. the purpose of this study is to evaluate the effectiveness of a complementary feed administered for 28 days for EGUS control. a gastroscopy (T0) was used to select sixteen horses with lesions on the squamous mucosa, graded between 0/4 and 4/4. a second gastroscopy was performed at the end of the supplementation (T1) to assess any changes in the lesions score. the data obtained did not reveal statistically significant differences that might enable us to objectively establish whether the product is effective in the case of these gastric pathologies. however, gastroscopic images showed a clear improvement in the lesions and in the appearance of the mucosa even in the absence of score variations, suggesting that 28 days of administration may not be sufficient for complete healing. during the trial the treated subjects displayed an improvement in behavior and appeared to be more relaxed and inclined to work. fhe results allow us to affirm that, despite not being statistically relevant, the feed supplement improved not only the appearance of the gastric mucosa, especially of the squamous mucosa, but also the well-being of the horses, making them more willing to work. further studies are needed, with an increased number of horses and a longer length of supplementation period.

Busechian, S., Catalano, C., Stratico, P., Gramenzi, A., Petrizzi, L., Orvieto, S., et al. (2023). Effectiveness of a complementary feed containing extract of Griffonia Simplicifolia and Olea Europaea on horses affected by equine gastric ulcer syndrome. LARGE ANIMALS REVIEW, 29(3), 155-162.

Effectiveness of a complementary feed containing extract of Griffonia Simplicifolia and Olea Europaea on horses affected by equine gastric ulcer syndrome

Busechian, S
;
2023-01-01

Abstract

equine gastric ulcer syndrome (EGUS) is a worldwide disease, found especially in racehorses, although it can affect different categories of animals with difference in prevalence. recently, two different diseases have been recognized, the first affecting the squamous mucosa (equine squamous gastric disease, ESGD) and the other the glandular mucosa (equine glandular gastric disease, EGGD), with different pathophysiology, risk factors and management. to date, the main strategy for the treatment involves acid-suppressive therapy with omeprazole, often associated with sucralfate; yet the total safety and absence of side effects of this treatment have recently been questioned. recently, an increasing number of studies have been investigating the use of complementary feeds to manage of these health issues. the purpose of this study is to evaluate the effectiveness of a complementary feed administered for 28 days for EGUS control. a gastroscopy (T0) was used to select sixteen horses with lesions on the squamous mucosa, graded between 0/4 and 4/4. a second gastroscopy was performed at the end of the supplementation (T1) to assess any changes in the lesions score. the data obtained did not reveal statistically significant differences that might enable us to objectively establish whether the product is effective in the case of these gastric pathologies. however, gastroscopic images showed a clear improvement in the lesions and in the appearance of the mucosa even in the absence of score variations, suggesting that 28 days of administration may not be sufficient for complete healing. during the trial the treated subjects displayed an improvement in behavior and appeared to be more relaxed and inclined to work. fhe results allow us to affirm that, despite not being statistically relevant, the feed supplement improved not only the appearance of the gastric mucosa, especially of the squamous mucosa, but also the well-being of the horses, making them more willing to work. further studies are needed, with an increased number of horses and a longer length of supplementation period.
2023
Pubblicato
Rilevanza nazionale
Articolo
Sì, ma tipo non specificato
Settore MVET-04/B - Clinica medica veterinaria
English
Griffonia simplicifolia
Olea europaea
ESGD
EGGD
gastric ulcers
Busechian, S., Catalano, C., Stratico, P., Gramenzi, A., Petrizzi, L., Orvieto, S., et al. (2023). Effectiveness of a complementary feed containing extract of Griffonia Simplicifolia and Olea Europaea on horses affected by equine gastric ulcer syndrome. LARGE ANIMALS REVIEW, 29(3), 155-162.
Busechian, S; Catalano, C; Stratico, P; Gramenzi, A; Petrizzi, L; Orvieto, S; Rueca, F
Articolo su rivista
File in questo prodotto:
File Dimensione Formato  
568-Article Text-3120-1-10-20230614.pdf

solo utenti autorizzati

Tipologia: Versione Editoriale (PDF)
Licenza: Copyright dell'editore
Dimensione 339.77 kB
Formato Adobe PDF
339.77 kB Adobe PDF   Visualizza/Apri   Richiedi una copia

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/403703
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 0
  • ???jsp.display-item.citation.isi??? 0
social impact