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EnglishOur aim was to evaluate the role of SPECT/CT for the diagnosis of diabetic foot infection by labeled leukocytes. Methods: Seventeen patients with 19 clinically suspected sites of infection were included. After leukocyte labeling and administration, planar scans were acquired at 30 min, 4 h, and 24 h for 18 consecutive patients. SPECT/CT was obtained at 6 h. The final diagnosis was established by clinical follow-up (24 mo) in all cases and by bone biopsy for 14 sites. Results: Leukocyte scanning was positive in 16 of 19 lesions and negative in 3. SPECT/CT changed the interpretation of the planar and SPECT images for 10 of 19 suspected sites (52.6%): it excluded osteomyelitis in 6 cases, revealed bone infection in 1 case, and revealed both bone and soft-tissue infection in 3 cases. The hybrid device did not significantly contribute to the evaluation of patients with negative scan results. Conclusion: SPECT/CT can be useful for a more accurate diagnosis of diabetic foot infection by labeled leukocyte imaging. Copyright © 2009 by the Society of Nuclear Medicine, Inc.
Filippi, L., Uccioli, L., Giurato, L., & Schillaci, O. (2009). Diabetic foot infection: Usefulness of SPECT/CT for 99mTc-HMPAO- labeled leukocyte imaging. THE JOURNAL OF NUCLEAR MEDICINE, 50(7), 1042-1046.
| Tipologia: | Articolo su rivista |
| Citazione: | Filippi, L., Uccioli, L., Giurato, L., & Schillaci, O. (2009). Diabetic foot infection: Usefulness of SPECT/CT for 99mTc-HMPAO- labeled leukocyte imaging. THE JOURNAL OF NUCLEAR MEDICINE, 50(7), 1042-1046. |
| IF: | Con Impact Factor ISI |
| Lingua: | English |
| Settore Scientifico Disciplinare: | Settore MED/13 - Endocrinologia |
| Revisione (peer review): | Sì, ma tipo non specificato |
| Tipo: | Articolo |
| Rilevanza: | Rilevanza internazionale |
| Digital Object Identifier (DOI): | http://dx.doi.org/10.2967/jnumed.108.059493 |
| Stato di pubblicazione: | Pubblicato |
| Data di pubblicazione: | 2009 |
| Titolo: | Diabetic foot infection: Usefulness of SPECT/CT for 99mTc-HMPAO- labeled leukocyte imaging |
| Autori: | |
| Autori: | Filippi,L; Uccioli,L; Giurato,L; Schillaci,O |
| Appare nelle tipologie: | 01 - Articolo su rivista |
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