Intrauterine growth restriction seems to be characterized by a high-resistance, low cardiac output state that is detectable at 22 to 24 weeks’ gestation in the preclinical stages of the disease.2 This cardiovascular profile seems to be present at different degrees of expression in the early and the late forms of the disease. The low cardiac output may be because of 2 main reasons, namely the hypovolemic state and the possible mechanical compression of the inferior vena cava. During physical activity, the blood flow may be redirected to the muscles. In case of normal plasma volume expansion and maternal cardiovascular performance, physical activity may have no effect on placental perfusion and fetal growth. If plasma volume is not adequate and cardiac output is lower than it should be, the redirection of part of the blood flow to the muscles might steal precious blood from the placenta.
Valensise, H., Novelli, G.p., Vasapollo, B. (2024). Restricted physical activity and maternal rest improve fetal growth: should we look for the reason in the cardiovascular modifications?. AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 1-2 [10.1016/j.ajog.2024.08.002].
Restricted physical activity and maternal rest improve fetal growth: should we look for the reason in the cardiovascular modifications?
Valensise H.;Vasapollo B.
2024-01-01
Abstract
Intrauterine growth restriction seems to be characterized by a high-resistance, low cardiac output state that is detectable at 22 to 24 weeks’ gestation in the preclinical stages of the disease.2 This cardiovascular profile seems to be present at different degrees of expression in the early and the late forms of the disease. The low cardiac output may be because of 2 main reasons, namely the hypovolemic state and the possible mechanical compression of the inferior vena cava. During physical activity, the blood flow may be redirected to the muscles. In case of normal plasma volume expansion and maternal cardiovascular performance, physical activity may have no effect on placental perfusion and fetal growth. If plasma volume is not adequate and cardiac output is lower than it should be, the redirection of part of the blood flow to the muscles might steal precious blood from the placenta.File | Dimensione | Formato | |
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