The emergence of vaccinomics and system vaccinology represents a transformative shift in immunization strategies, advocating for personalized vaccines tailored to individual genetic and immunological profiles. Integrating insights from genomics, transcriptomics, proteomics, and immunology, personalized vaccines offer the promise of enhanced efficacy and safety, revolutionizing the field of vaccinology. However, the development of personalized vaccines presents multifaceted challenges, including technical, ethical, economic, and regulatory considerations. Addressing these challenges is essential to ensure equitable access and safety of personalized vaccination strategies. Despite these hurdles, the potential of personalized vaccines to optimize responses and mitigate disease burden underscores the significance of ongoing research and collaboration in advancing precision medicine in immunization.

Montin, D., Santilli, V., Beni, A., Costagliola, G., Martire, B., Mastrototaro, M.f., et al. (2024). Towards personalized vaccines. FRONTIERS IN IMMUNOLOGY, 15, 1-11 [10.3389/fimmu.2024.1436108].

Towards personalized vaccines

Sgrulletti, Mayla;Moschese, Viviana
2024-01-01

Abstract

The emergence of vaccinomics and system vaccinology represents a transformative shift in immunization strategies, advocating for personalized vaccines tailored to individual genetic and immunological profiles. Integrating insights from genomics, transcriptomics, proteomics, and immunology, personalized vaccines offer the promise of enhanced efficacy and safety, revolutionizing the field of vaccinology. However, the development of personalized vaccines presents multifaceted challenges, including technical, ethical, economic, and regulatory considerations. Addressing these challenges is essential to ensure equitable access and safety of personalized vaccination strategies. Despite these hurdles, the potential of personalized vaccines to optimize responses and mitigate disease burden underscores the significance of ongoing research and collaboration in advancing precision medicine in immunization.
2024
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MEDS-20/A - Pediatria generale e specialistica
English
genomics
precision medicine
proteomics
system vaccinology
transcriptomics
vaccines
vaccinomics and personalized vaccines
Montin, D., Santilli, V., Beni, A., Costagliola, G., Martire, B., Mastrototaro, M.f., et al. (2024). Towards personalized vaccines. FRONTIERS IN IMMUNOLOGY, 15, 1-11 [10.3389/fimmu.2024.1436108].
Montin, D; Santilli, V; Beni, A; Costagliola, G; Martire, B; Mastrototaro, Mf; Ottaviano, G; Rizzo, C; Sgrulletti, M; Miraglia Del Giudice, M; Mosches...espandi
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/394483
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