Cushing syndrome (CS) is certainly one of the most challenging endocrine disorders. The greatest problem involves the differentiation between Cushing disease and ectopic ACTH syndrome. We report a patient with ACTH-dependent CS who elsewhere underwent unsuccessful transsphenoidal surgery for a pituitary microadenoma. In our institution, high resolution CT didn't show any chest tumor but laboratory data were consistent with ectopic ACTH secretion.Only In-111 Octreoscan, integrated with SPECT-CT and virtual bronchoscopy, allowed the diagnosis of ectopic Cushing syndrome due to occult bronchial carcinoid. Successful surgery was then performed. © 2009 by Lippincott Williams & Wilkins.

Corsello, S., Fintini, D., Lovicu, R., Paragliola, R., Rufini, V., Simonetti, G., et al. (2009). Ectopic ACTH syndrome due to occult bronchial carcinoid. CLINICAL NUCLEAR MEDICINE, 34(7), 459-461 [10.1097/RLU.0b013e3181a7d22e].

Ectopic ACTH syndrome due to occult bronchial carcinoid

SIMONETTI, GIOVANNI MARIA EGISTO;
2009-01-01

Abstract

Cushing syndrome (CS) is certainly one of the most challenging endocrine disorders. The greatest problem involves the differentiation between Cushing disease and ectopic ACTH syndrome. We report a patient with ACTH-dependent CS who elsewhere underwent unsuccessful transsphenoidal surgery for a pituitary microadenoma. In our institution, high resolution CT didn't show any chest tumor but laboratory data were consistent with ectopic ACTH secretion.Only In-111 Octreoscan, integrated with SPECT-CT and virtual bronchoscopy, allowed the diagnosis of ectopic Cushing syndrome due to occult bronchial carcinoid. Successful surgery was then performed. © 2009 by Lippincott Williams & Wilkins.
2009
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore MED/36 - DIAGNOSTICA PER IMMAGINI E RADIOTERAPIA
English
Con Impact Factor ISI
111 In-Octreoscan; Bilateral inferior petrosal sinus sampling; Bronchial carcinoid; Ectopic Cushing syndrome; SPECT-CT; Virtual bronchoscopy
Corsello, S., Fintini, D., Lovicu, R., Paragliola, R., Rufini, V., Simonetti, G., et al. (2009). Ectopic ACTH syndrome due to occult bronchial carcinoid. CLINICAL NUCLEAR MEDICINE, 34(7), 459-461 [10.1097/RLU.0b013e3181a7d22e].
Corsello, S; Fintini, D; Lovicu, R; Paragliola, R; Rufini, V; Simonetti, Gme; Pontecorvi, A
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/39223
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