Triple-reassortant swine influenza A (H1) viruses, containing genes from avian, human, and swine influenza viruses, emerged and became an outbreak among humans worldwide. Over a 1,000 cases were identified within the first month, chiefly in Mexico and the United States. Here, the phylogenetic analysis of haemagglutin (HA), neuraminidase (NA), and matrix protein (MP) was carried out. The analysis showed that the H1 of this reassortant originated from American pigs, while NA and MP were more likely from European pigs. All of the 2009 isolates appear homogeneous and cluster together, although they are distinct from classical human A (H1N1) viruses.

Babakir Mina, M., Dimonte, S., Perno, C.f., Ciotti, M. (2009). Origin of the 2009 Mexico influenza virus: a comparative phylogenetic analysis of the principal external antigens and matrix protein, 154(8), 1349-1352 [10.1007/s00705-009-0438-1].

Origin of the 2009 Mexico influenza virus: a comparative phylogenetic analysis of the principal external antigens and matrix protein

PERNO, CARLO FEDERICO;
2009-07-01

Abstract

Triple-reassortant swine influenza A (H1) viruses, containing genes from avian, human, and swine influenza viruses, emerged and became an outbreak among humans worldwide. Over a 1,000 cases were identified within the first month, chiefly in Mexico and the United States. Here, the phylogenetic analysis of haemagglutin (HA), neuraminidase (NA), and matrix protein (MP) was carried out. The analysis showed that the H1 of this reassortant originated from American pigs, while NA and MP were more likely from European pigs. All of the 2009 isolates appear homogeneous and cluster together, although they are distinct from classical human A (H1N1) viruses.
lug-2009
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore MED/07 - MICROBIOLOGIA E MICROBIOLOGIA CLINICA
English
Con Impact Factor ISI
hemagglutinin, human influenza A virus; HN protein; Influenza virus hemagglutinin; M1 protein, Influenza A virus; matrix protein; virus antigen; animal; article; classification; epidemic; Europe; genetic reassortment; genetics; human; influenza; Influenza virus A H1N1; Mexico; phylogeny; swine; United States; virology; Animals; Antigens, Viral; Disease Outbreaks; Europe; Hemagglutinin Glycoproteins, Influenza Virus; HN Protein; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Mexico; Phylogeny; Reassortant Viruses; Swine; United States; Viral Matrix Proteins
http://www.springerlink.com/content/q5227636lmw23h72/
Babakir Mina, M., Dimonte, S., Perno, C.f., Ciotti, M. (2009). Origin of the 2009 Mexico influenza virus: a comparative phylogenetic analysis of the principal external antigens and matrix protein, 154(8), 1349-1352 [10.1007/s00705-009-0438-1].
Babakir Mina, M; Dimonte, S; Perno, Cf; Ciotti, M
Articolo su rivista
File in questo prodotto:
File Dimensione Formato  
Origin of the 2009 Mexico influenza virus a comparative phylogenetic analysis of the principal external antigens and matrix protein.pdf

accesso aperto

Licenza: Creative commons
Dimensione 191.57 kB
Formato Adobe PDF
191.57 kB Adobe PDF Visualizza/Apri

Questo articolo è pubblicato sotto una Licenza Licenza Creative Commons Creative Commons

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/39183
Citazioni
  • ???jsp.display-item.citation.pmc??? 13
  • Scopus ND
  • ???jsp.display-item.citation.isi??? 23
social impact