a 57-year-old male with history of thalassemia intermedia and hepatocellular carcinoma underwent a positron emission tomography/computed tomography (PET/CT) scan with 18F-choline before radioembolization procedure with 90Y-microspheres. The PET/CT scan with 18F-choline demonstrated highly increased tracer incorporation within a gross lesion in the hepatic dome coupled with diffuse activity in bone marrow, this latter aspect was probably due to the compensatory hematopoiesis stimulation induced by chronic hemolysis. This pattern of skeletal 18F-choline uptake should be considered as a peculiar PET/CT finding in thalassemic patients.

Filippi, L. (2020). Increased bone marrow 18F-choline uptake in a patient with hepatocellular carcinoma and thalassemia intermedia. MOLECULAR IMAGING AND RADIONUCLIDE THERAPY, 29, 45-48 [10.4274/mirt.galenos.2019.03064].

Increased bone marrow 18F-choline uptake in a patient with hepatocellular carcinoma and thalassemia intermedia

Filippi L
2020-01-01

Abstract

a 57-year-old male with history of thalassemia intermedia and hepatocellular carcinoma underwent a positron emission tomography/computed tomography (PET/CT) scan with 18F-choline before radioembolization procedure with 90Y-microspheres. The PET/CT scan with 18F-choline demonstrated highly increased tracer incorporation within a gross lesion in the hepatic dome coupled with diffuse activity in bone marrow, this latter aspect was probably due to the compensatory hematopoiesis stimulation induced by chronic hemolysis. This pattern of skeletal 18F-choline uptake should be considered as a peculiar PET/CT finding in thalassemic patients.
2020
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MEDS-22/A - Diagnostica per immagini e radioterapia
English
18F-choline; positron emission tomography/computed tomography; hepatocellular carcinoma; thalassemia.
Filippi, L. (2020). Increased bone marrow 18F-choline uptake in a patient with hepatocellular carcinoma and thalassemia intermedia. MOLECULAR IMAGING AND RADIONUCLIDE THERAPY, 29, 45-48 [10.4274/mirt.galenos.2019.03064].
Filippi, L
Articolo su rivista
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/390572
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