Impact of STIs on cervical cancer screening: Prevalence of Chlamydia trachomatis and Neisseria gonorrhoeae in visual inspection with acetic acid (VIA) positive women in Mozambique

background cervical cancer, primarily from HPV, is prevalent in countries like mozambique, with HIV individuals at higher risk. the visual Inspection with acetic acid (VIA) screening method can be influenced by STIs like chlamydia trachomatis (CT) and neisseria gonorrhoeae (NG). this study examines CT and NG prevalence in HIV-positive and negative women using VIA in mozambique's DREAM program. methods In this cross-sectional research conducted at a DREAM program facility in maputo from 01/07/2021 to 31/05/2022, cervical specimens were taken from VIA-positive patients. CT/NG testing was performed using the cobas (R) 4800 DNA CT/NG test. statistical analyses focused on associations and prevalence rates, considering demographic, clinical, and exposure data. results among 117 women, we observed a CT prevalence of 6.8% (8/117) and an NG prevalence of 2.6%(3/117). no significant associations between CT/NG infection rates and factors such as age, HIV status, VIA results, or high-risk HPV (hrHPV) was observed. we found a 47% prevalence of hrHPV infections among participants with cervical lesions; no significant association between hrHPV and CT/NG infections was observed. conclusion this study highlights the prevalence of CT and NG in VIA-positive women in mozambique, emphasizing the STI burden and suggesting integration of STI screening in cervical cancer prevention strategies.