this review focuses on the immune checkpoint inhibitors (ICIs) in the context of breast cancer (BC) management. these innovative treatments, by targeting proteins expressed on both tumor and immune cells, aim to overcome tumor-induced immune suppression and reactivate the immune system. the potential of this approach is the subject of numerous clinical studies. here, we explore the key studies and emerging therapies related to ICIs providing a detailed analysis of their specific and combined use in BC treatment.

Rebaudi, F., De Franco, F., Goda, R., Obino, V., Vita, G., Baronti, C., et al. (2024). The landscape of combining immune checkpoint inhibitors with novel Therapies: Secret alliances against breast cancer. CANCER TREATMENT REVIEWS, 130 [10.1016/j.ctrv.2024.102831].

The landscape of combining immune checkpoint inhibitors with novel Therapies: Secret alliances against breast cancer

Melaiu O.;
2024-01-01

Abstract

this review focuses on the immune checkpoint inhibitors (ICIs) in the context of breast cancer (BC) management. these innovative treatments, by targeting proteins expressed on both tumor and immune cells, aim to overcome tumor-induced immune suppression and reactivate the immune system. the potential of this approach is the subject of numerous clinical studies. here, we explore the key studies and emerging therapies related to ICIs providing a detailed analysis of their specific and combined use in BC treatment.
2024
Pubblicato
Rilevanza internazionale
Review
Esperti anonimi
Settore MED/05
Settore MEDS-02/B - Patologia clinica
English
Breast cancer
Immune checkpoints
Immune checkpoints blockade
Immunotherapy
Targeted therapy
Rebaudi, F., De Franco, F., Goda, R., Obino, V., Vita, G., Baronti, C., et al. (2024). The landscape of combining immune checkpoint inhibitors with novel Therapies: Secret alliances against breast cancer. CANCER TREATMENT REVIEWS, 130 [10.1016/j.ctrv.2024.102831].
Rebaudi, F; De Franco, F; Goda, R; Obino, V; Vita, G; Baronti, C; Iannone, E; Pitto, F; Massa, B; Fenoglio, D; Jandus, C; Poggio, F; Fregatti, P; Mela...espandi
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/388305
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