purpose: to evaluate the long-term results associated with the zenith alpha thoracic stent-graft, which was designed to address challenging access vessel anatomy. materials and methods: a retrospective analysis was conducted of 44 consecutive patients (mean age 72.5±8.3 years; 25 men) treated in a single center between august 2010 and october 2014 with a minimum follow-up of 5 years in survivors. the zenith alpha thoracic stent-graft was used to treat thoracic aortic aneurysms (n=37), thoracoabdominal aortic aneurysm (n=5), or penetrating aortic ulcer (n=2). ten patients (23%) were American society of anesthesiologists class IV, and 9 (20%) had nonelective procedures. access vessel anatomy was demanding (mean minimum diameter 5.4 mm, tortuosity index 1.3). the primary endpoint at 5 years was ongoing clinical success (freedom from aneurysm-/procedure-related death, secondary intervention, type I or III endoleak, infection, thrombosis, aneurysm expansion, rupture, or conversion). secondary endpoints were freedom from all-cause mortality, device migration, stent fractures, fabric erosions, endoleaks, neurological events, and access vessel complications. results: the ongoing clinical success was 84% (37 of 44 patients) owing to 4 aneurysm-related deaths (9%), 3 type I or III endoleaks (1 in a deceased patient), and 1 aneurysm expansion without detectable endoleak. there were 3 access vessel complications (7%), and no postoperative neurological events. migration was observed in 2 cases (5%). there were no stent fractures or fabric tears. conclusion: despite the alterations in stent-graft design and material to reduce profile, the zenith alpha thoracic stent-graft showed favorable long-term results even in multimorbid patients with demanding iliac anatomy.

Beropoulis, E., Fazzini, S., Austermann, M., Torsello, G.b., Damerau, S., Torsello, G.f. (2020). Long-term results of thoracic endovascular aortic repair using a low-profile stent-graft. JOURNAL OF ENDOVASCULAR THERAPY, 28(1), 56-62 [10.1177/1526602820952416].

Long-term results of thoracic endovascular aortic repair using a low-profile stent-graft

Fazzini, S.;
2020-01-01

Abstract

purpose: to evaluate the long-term results associated with the zenith alpha thoracic stent-graft, which was designed to address challenging access vessel anatomy. materials and methods: a retrospective analysis was conducted of 44 consecutive patients (mean age 72.5±8.3 years; 25 men) treated in a single center between august 2010 and october 2014 with a minimum follow-up of 5 years in survivors. the zenith alpha thoracic stent-graft was used to treat thoracic aortic aneurysms (n=37), thoracoabdominal aortic aneurysm (n=5), or penetrating aortic ulcer (n=2). ten patients (23%) were American society of anesthesiologists class IV, and 9 (20%) had nonelective procedures. access vessel anatomy was demanding (mean minimum diameter 5.4 mm, tortuosity index 1.3). the primary endpoint at 5 years was ongoing clinical success (freedom from aneurysm-/procedure-related death, secondary intervention, type I or III endoleak, infection, thrombosis, aneurysm expansion, rupture, or conversion). secondary endpoints were freedom from all-cause mortality, device migration, stent fractures, fabric erosions, endoleaks, neurological events, and access vessel complications. results: the ongoing clinical success was 84% (37 of 44 patients) owing to 4 aneurysm-related deaths (9%), 3 type I or III endoleaks (1 in a deceased patient), and 1 aneurysm expansion without detectable endoleak. there were 3 access vessel complications (7%), and no postoperative neurological events. migration was observed in 2 cases (5%). there were no stent fractures or fabric tears. conclusion: despite the alterations in stent-graft design and material to reduce profile, the zenith alpha thoracic stent-graft showed favorable long-term results even in multimorbid patients with demanding iliac anatomy.
2020
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/22
Settore MEDS-13/B - Chirurgia vascolare
English
access vessel anatomy ; endoleak; iliac artery; low-profile stent-graft ; migration ; mortality; iliac artery ; low-profile stent-graft
thoracic aortic aneurysm; thoracic endovascular aortic repair; tortuosity ;vascular access; Aged; Aged, 80 and over; Aortic Aneurysm, Thoracic
Blood Vessel Prosthesis; Female; Humans; Male; Middle Aged; Prosthesis Design; Retrospective Studies;; Treatment Outcome
Blood Vessel Prosthesis Implantation; Endovascular Procedures; Stents
Beropoulis, E., Fazzini, S., Austermann, M., Torsello, G.b., Damerau, S., Torsello, G.f. (2020). Long-term results of thoracic endovascular aortic repair using a low-profile stent-graft. JOURNAL OF ENDOVASCULAR THERAPY, 28(1), 56-62 [10.1177/1526602820952416].
Beropoulis, E; Fazzini, S; Austermann, M; Torsello, Gb; Damerau, S; Torsello, Gf
Articolo su rivista
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/387463
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