pregnancy entails notable physiological alterations and hormonal fluctuations that affect the well-being of both the fetus and the mother. cardiovascular events and arrhythmias are a major concern during pregnancy, especially in women with comorbidities or a history of arrhythmias. this paper provides an overview of the prevalence, therapies, and prognoses of different types of arrhythmias during pregnancy. the administration of antiarrhythmic drugs (AADs) during pregnancy demands careful consideration because of their possible effect on the mother and fetus. AADs can cross the placenta or be present in breast milk, potentially leading to adverse effects such as teratogenicity, growth restriction, or premature birth. the safety profiles of different classes of AADs are discussed. Individualized treatment approaches and close monitoring of pregnant women prescribed AADs are essential to ensure optimal maternal and fetal outcomes.

Mariani, M.v., Pierucci, N., La Fazia, V.m., Cipollone, P., Micillo, M., D'Amato, A., et al. (2024). Antiarrhythmic Drug Use in Pregnancy: Considerations and Safety Profiles. JOURNAL OF CARDIOVASCULAR DEVELOPMENT AND DISEASE, 11(8) [10.3390/jcdd11080243].

Antiarrhythmic Drug Use in Pregnancy: Considerations and Safety Profiles

La Fazia V. M.;Ammirati G.;Perrone M. A.
2024-01-01

Abstract

pregnancy entails notable physiological alterations and hormonal fluctuations that affect the well-being of both the fetus and the mother. cardiovascular events and arrhythmias are a major concern during pregnancy, especially in women with comorbidities or a history of arrhythmias. this paper provides an overview of the prevalence, therapies, and prognoses of different types of arrhythmias during pregnancy. the administration of antiarrhythmic drugs (AADs) during pregnancy demands careful consideration because of their possible effect on the mother and fetus. AADs can cross the placenta or be present in breast milk, potentially leading to adverse effects such as teratogenicity, growth restriction, or premature birth. the safety profiles of different classes of AADs are discussed. Individualized treatment approaches and close monitoring of pregnant women prescribed AADs are essential to ensure optimal maternal and fetal outcomes.
2024
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/11
Settore M-EDF/01
Settore MEDS-07/B - Malattie dell'apparato cardiovascolare
Settore MEDF-01/A - Metodi e didattiche delle attività motorie
English
antiarrhythmic drugs
arrhythmia
pregnancy
Mariani, M.v., Pierucci, N., La Fazia, V.m., Cipollone, P., Micillo, M., D'Amato, A., et al. (2024). Antiarrhythmic Drug Use in Pregnancy: Considerations and Safety Profiles. JOURNAL OF CARDIOVASCULAR DEVELOPMENT AND DISEASE, 11(8) [10.3390/jcdd11080243].
Mariani, Mv; Pierucci, N; La Fazia, Vm; Cipollone, P; Micillo, M; D'Amato, A; Fanisio, F; Ammirati, G; Salagundla, N; Lavalle, C; Perrone, Ma
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/386246
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