Distinguishing injury patterns in fatal falls from heights versus pedestrian impacts: an autopsy study for differential diagnosis in ambiguous cases

this study investigated the injury patterns associated with fatal falls from heights compared to individuals struck by cars, aiming to enhance the differential diagnosis in ambiguous cases, where it is unclear whether the body fell from nearby building or was left on the street following a road traffic incident. a retrospective review of comprehensive forensic reports from the Institute of legal medicine of the university of rome "tor vergata" between 2012 and 2023 was conducted. the analysis included 232 cases, gathering data on internal organ injuries, skeletal fractures, external skin injuries, as well as pleural, peritoneal, and pericardial effusions. bilateral lung injuries were significantly more common in falls from height (33.3%) compared to pedestrians (13.6%, p < 0.001). liver injuries also occurred more frequently in fall victims (49.6%) than in pedestrians (28.2%, p < 0.001). skull fractures were more frequent in falls from height (68.2%) versus individuals struck by cars (55.3%, p = 0.044), while unilateral leg fractures were more common in pedestrians (28.2%) compared to fall victims (16.3%, p = 0.029). external injuries, notably to the head and legs, were more frequent in pedestrians. the "total Injured skin area" analysis revealed a significant discriminative power with an optimal cut-off of 84.2 cm(2), suggesting that injuries exceeding this threshold may be indicative of a pedestrian road fatality.