Neuropathic pain is one of the most frequent symptoms in neurological clinical practice. It is caused by a lesion or disease of the somatosensory system and encompasses a broad spectrum of pathologies ranging from peripheral polyneuropathies to central nervous system disorders. The diagnosis of neuropathic pain requires clinical and instrumental assessment, as a single symptom or diagnostic test is not always sufficient to identify neuropathic pain. Neuropathic pain is extremely disabling and difficult to treat, and patients often have to try several pharmacological agents alone or in combination before a significant level of pain relief is achieved. Gabapentinoids, serotonin reuptake norephrine, and tricyclic antidepressants are the first-line therapy for neuropathic pain.
Rocchi, C., Valeriani, M., Leo, R.d. (2023). Neuropathic pain. In Autonomic Disorders in Clinical Practice (pp. 335-351). Springer International Publishing [10.1007/978-3-031-43036-7_16].
Neuropathic pain
Rocchi C.;Valeriani M.;
2023-01-01
Abstract
Neuropathic pain is one of the most frequent symptoms in neurological clinical practice. It is caused by a lesion or disease of the somatosensory system and encompasses a broad spectrum of pathologies ranging from peripheral polyneuropathies to central nervous system disorders. The diagnosis of neuropathic pain requires clinical and instrumental assessment, as a single symptom or diagnostic test is not always sufficient to identify neuropathic pain. Neuropathic pain is extremely disabling and difficult to treat, and patients often have to try several pharmacological agents alone or in combination before a significant level of pain relief is achieved. Gabapentinoids, serotonin reuptake norephrine, and tricyclic antidepressants are the first-line therapy for neuropathic pain.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
