Aortic dissection is characterized by an acute phase of medial dissection and a subacute-chronic phase of vessel wall repair. Matrix metalloproteinases (MMPs), through degradation of extracellular matrix, may play an important role in these processes. Elevation of MMPs might represent an opportunity to diagnostically characterize acute or chronic aortic processes. We examined the potential diagnostic role of MMP-9 and MMP-2 in different phases of aortic dissection.
Sangiorgi, G., Trimarchi, S., Mauriello, A., Righini, P., Bossone, E., Suzuki, T., et al. (2006). Plasma levels of metalloproteinases-9 and -2 in the acute and subacute phases of type A and type B aortic dissection. JOURNAL OF CARDIOVASCULAR MEDICINE, 7(5), 307-315 [10.2459/01.JCM.0000223251.26988.c5].
Plasma levels of metalloproteinases-9 and -2 in the acute and subacute phases of type A and type B aortic dissection
SANGIORGI, GIUSEPPE;MAURIELLO, ALESSANDRO;
2006-05-01
Abstract
Aortic dissection is characterized by an acute phase of medial dissection and a subacute-chronic phase of vessel wall repair. Matrix metalloproteinases (MMPs), through degradation of extracellular matrix, may play an important role in these processes. Elevation of MMPs might represent an opportunity to diagnostically characterize acute or chronic aortic processes. We examined the potential diagnostic role of MMP-9 and MMP-2 in different phases of aortic dissection.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
